Cytotoxic indole alkaloids from Tabemaemontana officinalis
文献类型：期刊论文
| 作者 | Zhang, Bing-Jie; Teng, Xi-Feng; Bao, Mei-Fen; Zhong, Xiu-Hong; Ni, Ling; Cai, Xiang-Hai
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| 刊名 | PHYTOCHEMISTRY
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| 出版日期 | 2015-12-01 |
| 卷号 | 120页码:46-52 |
| 关键词 | Tabernaemontana officinalis Apocynaceae Monoterpenoid indole alkaloid Bisindole alkaloid Cytotoxicity |
| 英文摘要 | Continued interest in cytotoxic alkaloids resulted in the isolation of 37 alkaloids including 29 known monoterpenoid indole alkaloids from the aerial parts of Tabernaemontana officinalis. Of the remaining 8 alkaloids, six were bisindole alkaloids named taberdivarines A-F (1-6) and the two were monomers named taberdivarines G and H (7-8). Alkaloids 1 and 2 are voaphylline-vobasinyl type bisindole alkaloids, a structural type previously unknown, while 3-6 exhibited cytotoxicity against three human cancer cell lines HeLa, MCF-7, and SW480 with IC50 values ranging from 1.42 to 11.35 mu M. (C) 2014 Elsevier Ltd. All rights reserved. |
| 类目[WOS] | Biochemistry & Molecular Biology ; Plant Sciences |
| 研究领域[WOS] | Biochemistry & Molecular Biology ; Plant Sciences |
| 关键词[WOS] | TABERNAEMONTANA-CORYMBOSA ; BISINDOLE ALKALOIDS ; VOAPHYLLINE ; DIVARICATA ; TOXICITY ; LEAVES |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000366962700005 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/25344]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Zhang, Bing-Jie,Teng, Xi-Feng,Bao, Mei-Fen,et al. Cytotoxic indole alkaloids from Tabemaemontana officinalis[J]. PHYTOCHEMISTRY,2015,120:46-52. |
| APA | Zhang, Bing-Jie,Teng, Xi-Feng,Bao, Mei-Fen,Zhong, Xiu-Hong,Ni, Ling,&Cai, Xiang-Hai.(2015).Cytotoxic indole alkaloids from Tabemaemontana officinalis.PHYTOCHEMISTRY,120,46-52. |
| MLA | Zhang, Bing-Jie,et al."Cytotoxic indole alkaloids from Tabemaemontana officinalis".PHYTOCHEMISTRY 120(2015):46-52. |
入库方式： OAI收割
来源：昆明植物研究所
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