Chemical constituents from Euphorbia wallichii and their biological activities
文献类型：期刊论文
| 作者 | Yang,Da-Song; Peng,Wei-Bing; Yang,Yong-Ping; Liu,Ke-Chun; Li,Xiao-Li; Xiao,Wei-Lie |
| 刊名 | JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
 |
| 出版日期 | 2015-09-02 |
| 卷号 | 17期号:9页码:946-951 |
| 关键词 | Euphorbia wallichii diterpenoid wallichiioid A cytotoxicity antiangiogenic activities |
| 英文摘要 | One rare diterpenoid which was an unusual phorbol derivative possessing a 5-ene-7-oxo functional group, wallichiioid A (1), and 17 known compounds (2-18) were isolated from the aerial parts of Euphorbia wallichii. The structures and relative configuration of these compounds were elucidated on the basis of extensive spectroscopic interpretation. All the known compounds were isolated from E. wallichii for the first time. Diterpenoids 1-5 were tested for their cytotoxicity against five cancer cell lines (A-549, MCF-7, Hep G2, HeLa, and P388) and showed IC50 values in the range of 8.19-29.72g/mL. The antiangiogenic activities of diterpenoids 1-5 were also evaluated using a zebrafish model. |
| 类目[WOS] | Plant Sciences ; Chemistry, Applied ; Chemistry, Medicinal ; Pharmacology & Pharmacy |
| 研究领域[WOS] | Plant Sciences ; Chemistry ; Pharmacology & Pharmacy |
| 关键词[WOS] | PHORBOL ESTERS ; DITERPENOIDS |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000361969800010 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/25165]  |
| 专题 | 昆明植物研究所_资源植物与生物技术所级重点实验室 |
| 推荐引用方式 GB/T 7714 | Yang,Da-Song,Peng,Wei-Bing,Yang,Yong-Ping,et al. Chemical constituents from Euphorbia wallichii and their biological activities[J]. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,2015,17(9):946-951. |
| APA | Yang,Da-Song,Peng,Wei-Bing,Yang,Yong-Ping,Liu,Ke-Chun,Li,Xiao-Li,&Xiao,Wei-Lie.(2015).Chemical constituents from Euphorbia wallichii and their biological activities.JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,17(9),946-951. |
| MLA | Yang,Da-Song,et al."Chemical constituents from Euphorbia wallichii and their biological activities".JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH 17.9(2015):946-951. |
入库方式： OAI收割
来源：昆明植物研究所
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