Comparative study on the analytical performance of three waveforms for the determination of several aminoglycoside antibiotics with high performance liquid chromatography using amperometric detection
文献类型：会议论文
| 作者 | Cai, YQ; Cai, W; Cheng, J; Mou, SF; Lu, YQ |
| 出版日期 | 2005 |
| 会议名称 | 17th International Ion Chromatograhy Symposium |
| 会议日期 | SEP 20-23, 2004 |
| 会议地点 | Trier, GERMANY |
| 关键词 | waveforms amperometric detection ammoglycoside antibiotics high performance liquid chromatography |
| 英文摘要 | A preliminary comparative study was carried out on the analytical performances of a new six-potential waveform and other two detection waveforms, triple-potential waveform and quadruple-potential waveform. The analytical performances compared included signal response, background noise, signal/noise ratio and signal stability. Compared with triple-potential waveform, and quadruple-potential waveform, the new six-potential waveform had higher signal response, signal/noise ratio, and sensitivity. As for determination reproducibility, the six-potential waveform also exhibited a slightly better performance than the other two waveforms. Under the selected experimental conditions based on the six-potential waveform, there is a linear correlation between peak area and concentration over two to three orders of magnitude for nine aminoglycoside antibiotics with a correlation coefficients better than 0.998 and the detection limits measured as three times the peak height signal-to-noise ratio for the nine aminoglycoside antibiotics were in the range of 0.0198-0.889 mu g/mL. The proposed method had been used to analyze real gentamicin sulphate drug sample. (c) 2005 Elsevier B.V. All rights reserved. |
| ISSN号 | 0021-9673 |
| 源URL | [http://ir.rcees.ac.cn/handle/311016/24758]  |
| 专题 | 生态环境研究中心_环境化学与生态毒理学国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Cai, YQ,Cai, W,Cheng, J,et al. Comparative study on the analytical performance of three waveforms for the determination of several aminoglycoside antibiotics with high performance liquid chromatography using amperometric detection[C]. 见:17th International Ion Chromatograhy Symposium. Trier, GERMANY. SEP 20-23, 2004. |
入库方式： OAI收割
来源：生态环境研究中心
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