Tuning the Reactivity of Radical through a Triplet Diradical Cu(II) Intermediate in Radical Oxidative Cross-Coupling
文献类型：期刊论文
| 作者 | Zhou, Liangliang1; Yi, Hong1; Zhu, Lei3; Qi, Xiaotian3; Jiang, Hanpeng4; Liu, Chao1 ; Feng, Yuqi4; Lan, Yu3; Lei AW(雷爱文)1,2
|
| 刊名 | Scientific Reports
 |
| 出版日期 | 2015 |
| 卷号 | 5页码:15934(1-12) |
| ISSN号 | 2045-2322 |
| 通讯作者 | 雷爱文 |
| 英文摘要 | Highly selective radical/radical cross-coupling is paid more attention in bond formations. However, due to their intrinsic active properties, radical species are apt to achieve homo-coupling instead of cross-coupling, which makes the selective cross-coupling as a great challenge and almost untouched. Herein a notable strategy to accomplish direct radical/radical oxidative cross-coupling has been demonstrated, that is metal tuning a transient radical to a persistent radical intermediate followed by coupling with another transient radical. Here, a transient nitrogen-centered radical is tuned to a persistent radical complex by copper catalyst, followed by coupling with a transient allylic carbon-centered radical. Firstly, nitrogen-centered radical generated from N-methoxybenzamide stabilized by copper catalyst was successfully observed by EPR. Then DFT calculations revealed that a triplet diradical Cu(II) complex formed from the chelation N-methoxybenzamide nitrogen-centered radical to Cu(II) is a persistent radical species. Moreover, conceivable nitrogen-centered radical Cu(II) complex was observed by high-resolution electrospray ionization mass spectrometry (ESI-MS). Ultimately, various allylic amides derivatives were obtained in good yields by adopting this strategy, which might inspire a novel and promising landscape in radical chemistry. |
| 学科主题 | 物理化学与绿色催化 |
| 收录类别 | SCI |
| 资助信息 | the 973 Program (2012CB725302);the National Natural Science Foundation of China (21390400;21272180;21302148);the Research Fund for the Doctoral Program of Higher Education of China (20120141130002);the Ministry of Science and Technology of China (2012YQ120060);The Program of Introducing Talents of Discipline to Universities of China (111 Program);the Foundation of 100 Young Chongqing University (project 0903005203191) |
| 语种 | 英语 |
| WOS记录号 | WOS:000363964900001 |
| 源URL | [http://210.77.64.217/handle/362003/19064]  |
| 专题 | 兰州化学物理研究所_OSSO国家重点实验室 |
| 作者单位 | 1.Wuhan Univ, Inst Adv Studies, Coll Chem & Mol Sci, Wuhan 430072, Hubei, Peoples R China 2.Chinese Acad Sci, Lanzhou Inst Chem Phys, State Key Lab Oxo Synth & Select Oxidat, Lanzhou 730000, Peoples R China 3.Chongqing Univ, Sch Chem & Chem Engn, Chongqing 400030, Peoples R China 4.Wuhan Univ, Coll Chem & Mol Sci, Wuhan 430072, Hubei, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhou, Liangliang,Yi, Hong,Zhu, Lei,et al. Tuning the Reactivity of Radical through a Triplet Diradical Cu(II) Intermediate in Radical Oxidative Cross-Coupling[J]. Scientific Reports,2015,5:15934(1-12). |
| APA | Zhou, Liangliang.,Yi, Hong.,Zhu, Lei.,Qi, Xiaotian.,Jiang, Hanpeng.,...&Lei AW.(2015).Tuning the Reactivity of Radical through a Triplet Diradical Cu(II) Intermediate in Radical Oxidative Cross-Coupling.Scientific Reports,5,15934(1-12). |
| MLA | Zhou, Liangliang,et al."Tuning the Reactivity of Radical through a Triplet Diradical Cu(II) Intermediate in Radical Oxidative Cross-Coupling".Scientific Reports 5(2015):15934(1-12). |
入库方式： OAI收割
来源：兰州化学物理研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。