NMP and O-2 as Radical Initiator: Trifluoromethylation of Alkenes to Tertiary beta-Trifluoromethyl Alcohols at Room Temperature
文献类型：期刊论文
| 作者 | Liu C(刘超)1; Lu, Qingquan1; Huang, Zhiyuan1; Zhang, Jian1; Liao, Fan3; Peng, Pan1; Lei AW(雷爱文)1,2 |
| 刊名 | Organic Letters
 |
| 出版日期 | 2015 |
| 卷号 | 17期号:24页码:6034-6037 |
| ISSN号 | 1523-7060 |
| 通讯作者 | 雷爱文 |
| 英文摘要 | A novel strategy was developed to trigger ·CF3 by using in situ generated peroxide in NMP under O2 or air as the radical initiator. Radical trifluoromethylation of alkenes was achieved toward tertiary β-trifluoromethyl alcohols. Various tertiary β-trifluoromethyl alcohols can be synthesized in good yields without extra oxidants or transition metal catalysts. Preliminary mechanistic investigation revealed that O2 diffusion can influence the reaction rate. |
| 学科主题 | 物理化学与绿色催化 |
| 收录类别 | SCI |
| 资助信息 | the 973 Program (2012CB725302;2011CB808600);the National Natural Science Foundation of China (21390400;21520102003;21272180;21302148);the Research Fund for the Doctoral Program of Higher Education of China (20120141130002);the Ministry of Science and Technology of China (2012YQ120060);The Program of Introducing Talents of Discipline to Universities of China (111 Program) |
| 语种 | 英语 |
| WOS记录号 | WOS:000366878300025 |
| 源URL | [http://210.77.64.217/handle/362003/19197]  |
| 专题 | 兰州化学物理研究所_OSSO国家重点实验室 |
| 作者单位 | 1.Wuhan Univ, Coll Chem & Mol Sci, IAS, Wuhan 430072, Hubei, Peoples R China 2.Chinese Acad Sci, Lanzhou Inst Chem Phys, State Key Lab Oxo Synth & Select Oxidat, Lanzhou 730000, Peoples R China 3.Jiangxi Normal Univ, Natl Res Ctr Carbohydrate Synth, Nanchang 330022, Jiangxi, Peoples R China |
| 推荐引用方式 GB/T 7714 | Liu C,Lu, Qingquan,Huang, Zhiyuan,et al. NMP and O-2 as Radical Initiator: Trifluoromethylation of Alkenes to Tertiary beta-Trifluoromethyl Alcohols at Room Temperature[J]. Organic Letters,2015,17(24):6034-6037. |
| APA | Liu C.,Lu, Qingquan.,Huang, Zhiyuan.,Zhang, Jian.,Liao, Fan.,...&Lei AW.(2015).NMP and O-2 as Radical Initiator: Trifluoromethylation of Alkenes to Tertiary beta-Trifluoromethyl Alcohols at Room Temperature.Organic Letters,17(24),6034-6037. |
| MLA | Liu C,et al."NMP and O-2 as Radical Initiator: Trifluoromethylation of Alkenes to Tertiary beta-Trifluoromethyl Alcohols at Room Temperature".Organic Letters 17.24(2015):6034-6037. |
入库方式： OAI收割
来源：兰州化学物理研究所
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