Synthesis of Luminescent Graphene Quantum Dots with High Quantum Yield and Their Toxicity Study
文献类型：期刊论文
| 作者 | Jiang, Dan1,2; Chen, Yunping1,2; Li, Na1; Li, Wen1; Wang, Zhenguo1,3; Zhu, Jingli1; Zhang H(张红)3; Liu B(刘斌)1; Xu S(许珊)2 ; Xu S(许珊)
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| 刊名 | PLoS ONE
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| 出版日期 | 2015 |
| 卷号 | 10期号:12页码:e0144906 |
| ISSN号 | 1932-6203 |
| 通讯作者 | 刘斌 ; 许珊 |
| 英文摘要 | High fluorescence quantum yield graphene quantum dots (GQDs) have showed up as a new generation for bioimaging. In this work, luminescent GQDs were prepared by an ameliorative photo-Fenton reaction and a subsequent hydrothermal process using graphene oxide sheets as the precursor. The as-prepared GQDs were nanomaterials with size ranging from 2.3 to 6.4 nm and emitted intense green luminescence in water. The fluorescence quantum yield was as high as 24.6%(excited at 340 nm) and the fluorescence was strongest at pH 7. Moreover, the influences of low-concentration (12.5, 25 mu g/mL) GQDs on the morphology, viability, membrane integrity, internal cellular reactive oxygen species level and mortality of HeLa cells were relatively weak, and the in vitro imaging demonstrated GQDs were mainly in the cytoplasm region. More strikingly, zebrafish embryos were co-cultured with GQDs for in vivo imaging, and the results of heart rate test showed the intake of small amounts of GQDs brought little harm to the cardiovascular of zebrafish. GQDs with high quantum yield and strong photoluminescence show good biocompatibility, thus they show good promising for cell imaging, biolabeling and other biomedical applications. |
| 学科主题 | 物理化学与绿色催化 |
| 收录类别 | SCI |
| 资助信息 | the Nature Science Foundations of China (21103205). |
| 语种 | 英语 |
| WOS记录号 | WOS:000367451400015 |
| 源URL | [http://210.77.64.217/handle/362003/19222]  |
| 专题 | 兰州化学物理研究所_OSSO国家重点实验室 |
| 通讯作者 | Xu S(许珊) |
| 作者单位 | 1.Lanzhou Univ, Sch Stomatol, Lanzhou 730000, Peoples R China 2.Chinese Acad Sci, Lanzhou Inst Chem Phys, State Key Lab Oxo Synth & Select, Lanzhou 730000, Peoples R China 3.Chinese Acad Sci, Inst Modern Phys, Dept Heavy Ion Radiat Med, Lanzhou, Peoples R China |
| 推荐引用方式 GB/T 7714 | Jiang, Dan,Chen, Yunping,Li, Na,et al. Synthesis of Luminescent Graphene Quantum Dots with High Quantum Yield and Their Toxicity Study[J]. PLoS ONE,2015,10(12):e0144906. |
| APA | Jiang, Dan.,Chen, Yunping.,Li, Na.,Li, Wen.,Wang, Zhenguo.,...&许珊.(2015).Synthesis of Luminescent Graphene Quantum Dots with High Quantum Yield and Their Toxicity Study.PLoS ONE,10(12),e0144906. |
| MLA | Jiang, Dan,et al."Synthesis of Luminescent Graphene Quantum Dots with High Quantum Yield and Their Toxicity Study".PLoS ONE 10.12(2015):e0144906. |
入库方式： OAI收割
来源：兰州化学物理研究所
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