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Contrast-dependent orientation discrimination in the mouse
文献类型：期刊论文
| 作者 | Long, MH; Jiang, WQ; Liu, DC; Yao, HS |
| 刊名 | SCIENTIFIC REPORTS
 |
| 出版日期 | 2015 |
| 卷号 | 5期号:1页码:15830-15830 |
| 关键词 | PRIMARY VISUAL-CORTEX MACAQUE V1 NEURONS RECEPTIVE-FIELD STRIATE CORTEX GAIN-CONTROL SPATIAL DISCRIMINATIONS SINGLE NEURONS BEHAVING MOUSE MOTION CAT |
| 通讯作者 | Yao, HS (reprint author), Chinese Acad Sci, Shanghai Inst Biol Sci, Inst Neurosci, Shanghai 200031, Peoples R China.,haishanyao@ion.ac.cn |
| 英文摘要 | As an important animal model to study the relationship between behaviour and neural activity, the mouse is able to perform a variety of visual tasks, such as orientation discrimination and contrast detection. However, it is not clear how stimulus contrast influences the performance of orientation discrimination in mice. In this study, we used two task designs, two-alternative forced choice (2AFC) and go/no-go, to examine the performance of mice to discriminate two orthogonal orientations at different contrasts. We found that the performance tended to increase with contrast, and the performance at high contrast was better when the stimulus set contained a single contrast than multiple contrasts. Physiological experiments in V1 showed that neural discriminability of two orthogonal orientations increased with contrast. Furthermore, orientation discriminability of V1 neurons at high contrast was higher in the single than in the multiple contrast condition, largely due to smaller response variance in the single contrast condition. Thus, the performance of mice to discriminate orientations at high contrast is adapted to the contrast range in the stimuli, partly attributed to the contrast-range dependent capacity of V1 neurons to discriminate orientations. |
| 学科主题 | Multidisciplinary Sciences |
| WOS标题词 | Science & Technology - Other Topics |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000363626000001 |
| 公开日期 | 2016-02-26 |
| 源URL | [http://ir.sibs.ac.cn/handle/331001/3928]  |
| 专题 | 上海神经科学研究所_神经所(总) |
| 推荐引用方式 GB/T 7714 | Long, MH,Jiang, WQ,Liu, DC,et al. Contrast-dependent orientation discrimination in the mouse[J]. SCIENTIFIC REPORTS,2015,5(1):15830-15830. |
| APA | Long, MH,Jiang, WQ,Liu, DC,&Yao, HS.(2015).Contrast-dependent orientation discrimination in the mouse.SCIENTIFIC REPORTS,5(1),15830-15830. |
| MLA | Long, MH,et al."Contrast-dependent orientation discrimination in the mouse".SCIENTIFIC REPORTS 5.1(2015):15830-15830. |
入库方式： OAI收割
来源：上海神经科学研究所
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