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Intron-based genomic editing: a highly efficient method for generating knockin zebrafish
文献类型：期刊论文
| 作者 | Li, J; Zhang, BB; Bu, JW; Du, JL |
| 刊名 | ONCOTARGET
 |
| 出版日期 | 2015 |
| 卷号 | 6期号:20页码:17891-17894 |
| 关键词 | CRISPR/CAS9 SYSTEM HOMOLOGOUS RECOMBINATION PRECISE EMBRYOS NUCLEASE MICE |
| 通讯作者 | Li, J (reprint author), Chinese Acad Sci, Shanghai Inst Biol Sci, Inst Neurosci, State Key Lab Neurosci,CAS Ctr Excellence Brain S, Shanghai 200031, Peoples R China.,lijia@ion.ac.cn ; forestdu@ion.ac.cn |
| 英文摘要 | The TALEN and CRISPR/Cas9 nuclease systems have been extensively utilized in genomic engineering of model organisms. In zebrafish, the nuclease systems have been successfully applied in generating loss-of-function knockout lines. However, genome-specific knockin techniques in zebrafish are still at the beginning. In this perspective, we briefly summarize the recent progresses on knockin approaches in zebrafish with a special focus on the newly developed intron-based knockin method. |
| WOS标题词 | Oncology ; Cell Biology |
| 学科主题 | Oncology; Cell Biology |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000359014700013 |
| 公开日期 | 2016-02-26 |
| 源URL | [http://ir.sibs.ac.cn/handle/331001/3941]  |
| 专题 | 上海神经科学研究所_神经所(总) |
| 推荐引用方式 GB/T 7714 | Li, J,Zhang, BB,Bu, JW,et al. Intron-based genomic editing: a highly efficient method for generating knockin zebrafish[J]. ONCOTARGET,2015,6(20):17891-17894. |
| APA | Li, J,Zhang, BB,Bu, JW,&Du, JL.(2015).Intron-based genomic editing: a highly efficient method for generating knockin zebrafish.ONCOTARGET,6(20),17891-17894. |
| MLA | Li, J,et al."Intron-based genomic editing: a highly efficient method for generating knockin zebrafish".ONCOTARGET 6.20(2015):17891-17894. |
入库方式： OAI收割
来源：上海神经科学研究所
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