Effects of activating transcription factor 4 deficiency on carbohydrate and lipid metabolism in mammals
文献类型：期刊论文
| 作者 | Wang, Chunxia; Guo, Feifan（郭非凡）
|
| 刊名 | IUBMB LIFE
 |
| 出版日期 | 2012 |
| 卷号 | 64期号:3页码:226-230 |
| 关键词 | ATF4 lipid metabolism energy homeostasis insulin secretion and sensitivity glucose metabolism |
| 通讯作者 | Guo, FF (reprint author), Chinese Acad Sci, Inst Nutr Sci, Shanghai Inst Biol Sci, Key Lab Nutr & Metab,Grad Sch, 294 Taiyuan Rd, Shanghai 200031, Peoples R China. |
| 英文摘要 | It has been shown that the mammalian activating transcription factor 4 (ATF4) is involved in many different physiological events, such as eye development, stress response, learning, and memory. However, several recent studies have demonstrated that ATF4 also plays an important role in the regulation of lipid and glucose metabolism, energy homeostasis, insulin secretion, and sensitivity, suggesting that ATF4 is a master regulator of metabolism. This review summarizes the most recent progress in the understanding of the novel roles of ATF4 in the regulation of metabolism. (c) 2012 IUBMB IUBMB Life, 2012. |
| 类目[WOS] | Biochemistry & Molecular Biology ; Cell Biology |
| 研究领域[WOS] | Biochemistry & Molecular Biology ; Cell Biology |
| 关键词[WOS] | ENDOPLASMIC-RETICULUM STRESS ; ASPARAGINE SYNTHETASE GENE ; CAMP-RESPONSE ELEMENTS ; ER STRESS ; TARGETED DISRUPTION ; ATF4 ; RESISTANCE ; MICE ; HOMEOSTASIS ; EXPRESSION |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000300668200003 |
| 公开日期 | 2016-02-26 |
| 版本 | 出版稿 |
| 源URL | [http://202.127.25.144/handle/331004/434]  |
| 专题 | 中国科学院上海生命科学研究院营养科学研究所_代谢的遗传与营养调控研究组 |
| 推荐引用方式 GB/T 7714 | Wang, Chunxia,Guo, Feifan. Effects of activating transcription factor 4 deficiency on carbohydrate and lipid metabolism in mammals[J]. IUBMB LIFE,2012,64(3):226-230. |
| APA | Wang, Chunxia,&Guo, Feifan.(2012).Effects of activating transcription factor 4 deficiency on carbohydrate and lipid metabolism in mammals.IUBMB LIFE,64(3),226-230. |
| MLA | Wang, Chunxia,et al."Effects of activating transcription factor 4 deficiency on carbohydrate and lipid metabolism in mammals".IUBMB LIFE 64.3(2012):226-230. |
入库方式： OAI收割
来源：上海营养与健康研究所
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