Application of Carbon Nanomaterials in Gene Delivery for Endogenous RNA Interference In Vitro and In Vivo
文献类型：期刊论文
| 作者 | Li, LY; Wen, YL; Xu, Q; Xu, L; Liu, D; Liu, G; Huang, Q |
| 刊名 | CURRENT PHARMACEUTICAL DESIGN
 |
| 出版日期 | 2015 |
| 卷号 | 21期号:22页码:3191—3198 |
| 关键词 | EFFICIENT INTRACELLULAR DELIVERY CATIONIC TETRAAMINO FULLERENE FUNCTIONALIZED GRAPHENE OXIDE DRUG-DELIVERY SIRNA DELIVERY BIOMEDICAL APPLICATIONS PHOTOTHERMAL THERAPY BIOSENSING PLATFORM CELLULAR DELIVERY MOLECULAR BEACON |
| ISSN号 | 1381-6128 |
| 通讯作者 | Liu, G (reprint author), Shanghai Inst Measurement & Testing Technol, Shanghai 201800, Peoples R China. |
| 英文摘要 | Knocking down expression by small interfering RNA (siRNA) has shown high affinity, specificity and potency in silencing target gene sites. For effective endogenous RNA interference (RNAi), proper siRNA delivery vehicles are essential, to take the siRNA inside cells and protect them during the circulation. Carbon nanomaterials (CNMs) have been successfully applied in biomedicine and biosensor based on their ultra-high surface functionalization and nucleic acid molecular loading capacity. Recently, CNMs have drawn considerable research interest and expectation as potential non-viral vectors for siRNA delivery. Here we reviewed the recent application of CNMs in gene delivery for RNAi, mainly about fullerenes, carbon nanotubes (CNTs) and graphene. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000357937500014 |
| 公开日期 | 2016-03-08 |
| 源URL | [http://ir.sinap.ac.cn/handle/331007/24866]  |
| 专题 | 上海应用物理研究所_中科院上海应用物理研究所2011-2017年 |
| 推荐引用方式 GB/T 7714 | Li, LY,Wen, YL,Xu, Q,et al. Application of Carbon Nanomaterials in Gene Delivery for Endogenous RNA Interference In Vitro and In Vivo[J]. CURRENT PHARMACEUTICAL DESIGN,2015,21(22):3191—3198. |
| APA | Li, LY.,Wen, YL.,Xu, Q.,Xu, L.,Liu, D.,...&Huang, Q.(2015).Application of Carbon Nanomaterials in Gene Delivery for Endogenous RNA Interference In Vitro and In Vivo.CURRENT PHARMACEUTICAL DESIGN,21(22),3191—3198. |
| MLA | Li, LY,et al."Application of Carbon Nanomaterials in Gene Delivery for Endogenous RNA Interference In Vitro and In Vivo".CURRENT PHARMACEUTICAL DESIGN 21.22(2015):3191—3198. |
入库方式： OAI收割
来源：上海应用物理研究所
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