Reversible Regulation of Catalytic Activity of Gold Nanoparticles with DNA Nanomachines
文献类型：期刊论文
| 作者 | Zhou, PP; Jia, SS; Pan, D; Wang, LH; Gao, JM; Lu, JX; Shi, JY; Tang, ZS; Liu, HJ |
| 刊名 | SCIENTIFIC REPORTS
 |
| 出版日期 | 2015 |
| 卷号 | 5页码:— |
| 关键词 | ENZYME CASCADE REACTION MACHINE COMPLEX NANOTECHNOLOGY HYBRIDIZATION SELECTIVITY MIMICKING CHEMISTRY DEVICES GROWTH |
| ISSN号 | 2045-2322 |
| 通讯作者 | Tang, ZS (reprint author), Shanghai Jiao Tong Univ, Shanghai Key Lab Stomatol, Sch Med, Peoples Hosp 9,Dept Endodont, Shanghai 200011, Peoples R China. |
| 英文摘要 | Reversible catalysis regulation has gained much attention and traditional strategies utilized reversible ligand coordination for switching catalyst's conformations. However, it remains challenging to regulate the catalytic activity of metal nanoparticle-based catalysts. Herein, we report a new DNA nanomachine-driven reversible nano-shield strategy for circumventing this problem. The basic idea is based on the fact that the conformational change of surface-attached DNA nanomachines will cause the variation of the exposed surface active area on metal nanoparticles. As a proof-of-concept study, we immobilized G-rich DNA strands on gold nanoparticles (AuNPs) which have glucose oxidase (GOx) like activity. Through the reversible conformational change of the G-rich DNA between a flexible single-stranded form and a compact G-quadruplex form, the catalytic activity of AuNPs has been regulated reversibly for several cycles. This strategy is reliable and robust, which demonstrated the possibility of reversibly adjusting catalytic activity with external surface coverage switching, rather than coordination interactions. |
| 语种 | 英语 |
| WOS记录号 | WOS:000361598200001 |
| 公开日期 | 2016-03-08 |
| 源URL | [http://ir.sinap.ac.cn/handle/331007/25032]  |
| 专题 | 上海应用物理研究所_中科院上海应用物理研究所2011-2017年 |
| 推荐引用方式 GB/T 7714 | Zhou, PP,Jia, SS,Pan, D,et al. Reversible Regulation of Catalytic Activity of Gold Nanoparticles with DNA Nanomachines[J]. SCIENTIFIC REPORTS,2015,5:—. |
| APA | Zhou, PP.,Jia, SS.,Pan, D.,Wang, LH.,Gao, JM.,...&Liu, HJ.(2015).Reversible Regulation of Catalytic Activity of Gold Nanoparticles with DNA Nanomachines.SCIENTIFIC REPORTS,5,—. |
| MLA | Zhou, PP,et al."Reversible Regulation of Catalytic Activity of Gold Nanoparticles with DNA Nanomachines".SCIENTIFIC REPORTS 5(2015):—. |
入库方式： OAI收割
来源：上海应用物理研究所
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