Technical Note: Synchrotron-based high-energy x-ray phase sensitive microtomography for biomedical research
文献类型：期刊论文
| 作者 | Liu, HQ; Wu, XZ; Xiao, TQ |
| 刊名 | MEDICAL PHYSICS
 |
| 出版日期 | 2015 |
| 卷号 | 42期号:10页码:5595—5603 |
| 关键词 | ATTENUATION DUALITY CONTRAST TOMOGRAPHY FRESNEL REGION SOFT-TISSUE RETRIEVAL HOLOTOMOGRAPHY INTERFEROMETER OBJECT IMAGE |
| ISSN号 | 0094-2405 |
| 通讯作者 | Wu, XZ (reprint author), Univ Alabama Birmingham, Dept Radiol, Birmingham, AL 35249 USA. |
| 英文摘要 | Purpose: Propagation-based phase-contrast CT (PPCT) utilizes highly sensitive phase-contrast technology applied to x-ray microtomography. Performing phase retrieval on the acquired angular projections can enhance image contrast and enable quantitative imaging. In this work, the authors demonstrate the validity and advantages of a novel technique for high-resolution PPCT by using the generalized phase-attenuation duality (PAD) method of phase retrieval. Methods: A high-resolution angular projection data set of a fish head specimen was acquired with a monochromatic 60-keV x-ray beam. In one approach, the projection data were directly used for tomographic reconstruction. In two other approaches, the projection data were preprocessed by phase retrieval based on either the linearized PAD method or the generalized PAD method. The reconstructed images from all three approaches were then compared in terms of tissue contrast-to-noise ratio and spatial resolution. Results: The authors' experimental results demonstrated the validity of the PPCT technique based on the generalized PAD-based method. In addition, the results show that the authors' technique is superior to the direct PPCT technique as well as the linearized PAD-based PPCT technique in terms of their relative capabilities for tissue discrimination and characterization. Conclusions: This novel PPCT technique demonstrates great potential for biomedical imaging, especially for applications that require high spatial resolution and limited radiation exposure. (C) 2015 American Association of Physicists in Medicine. |
| 语种 | 英语 |
| WOS记录号 | WOS:000362570100003 |
| 公开日期 | 2016-03-08 |
| 源URL | [http://ir.sinap.ac.cn/handle/331007/25069]  |
| 专题 | 上海应用物理研究所_中科院上海应用物理研究所2011-2017年 |
| 推荐引用方式 GB/T 7714 | Liu, HQ,Wu, XZ,Xiao, TQ. Technical Note: Synchrotron-based high-energy x-ray phase sensitive microtomography for biomedical research[J]. MEDICAL PHYSICS,2015,42(10):5595—5603. |
| APA | Liu, HQ,Wu, XZ,&Xiao, TQ.(2015).Technical Note: Synchrotron-based high-energy x-ray phase sensitive microtomography for biomedical research.MEDICAL PHYSICS,42(10),5595—5603. |
| MLA | Liu, HQ,et al."Technical Note: Synchrotron-based high-energy x-ray phase sensitive microtomography for biomedical research".MEDICAL PHYSICS 42.10(2015):5595—5603. |
入库方式： OAI收割
来源：上海应用物理研究所
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