Evaluation of the in vitro estrogenicity of emerging bisphenol analogs and their respective estrogenic contributions in municipal sewage sludge in China
文献类型：期刊论文
| 作者 | Ruan, Ting; Liang, Dong; Song, Shanjun; Song, Maoyong; Wang, Hailin; Jiang, Guibin |
| 刊名 | CHEMOSPHERE
 |
| 出版日期 | 2015-04 |
| 卷号 | 124页码:150-155 |
| 关键词 | Bisphenols Estrogenic activity BLYES assay Sewage sludge |
| 英文摘要 | There is a potential risk to the environment from persistent estrogenic compounds in sewage sludge. In this study, eight bisphenols (BPs) were identified in sewage sludge collected from wastewater treatment plants in 15 cities in China. The estrogenic potencies of the eight BPs and the estrogenic activities of sludge samples were evaluated using a bioluminescence yeast estrogen screen (BLYES) assay. All sludge samples elicited considerable estrogenic activity at a range of 2.8-4.7 ng E2 g(-1) dry weight (dw). All BPs exhibited estrogenic activity in the BLYES assay, but there were significant differences between the potency of individual chemicals. Bisphenol AF had the highest activity, followed by tetrachlorobisphenol A, bisphenol F, bisphenol A, bisphenol E, bisphenol S and 2,4-dihydroxybenzophenone. Tetrabromobisphenol A showed weak estrogenic activity at 1 x 10(4) nM, but significant cytotoxicity above this concentration. The total estradiol equivalency quantities (EEQs) of BPs were in the range of 2.16-49.13 pg E2 g(-1) dw, accounting for 0.05-1.47% of the total EEQs in sewage sludge samples. The results indicate that BPs made a minor contribution to the estrogenic activity of the investigated sewage sludge. Nevertheless, our results suggest that considerable attention should be directed to the estrogenic potentials of emerging organic pollutants because of their widespread use and their potential to persist in the environment. (C) 2014 Elsevier Ltd. All rights reserved. |
| 研究领域[WOS] | Environmental Sciences |
| WOS记录号 | WOS:000349267100020 |
| 公开日期 | 2016-03-15 |
| 源URL | [http://ir.rcees.ac.cn/handle/311016/32572]  |
| 专题 | 生态环境研究中心_环境化学与生态毒理学国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Ruan, Ting,Liang, Dong,Song, Shanjun,et al. Evaluation of the in vitro estrogenicity of emerging bisphenol analogs and their respective estrogenic contributions in municipal sewage sludge in China[J]. CHEMOSPHERE,2015,124:150-155. |
| APA | Ruan, Ting,Liang, Dong,Song, Shanjun,Song, Maoyong,Wang, Hailin,&Jiang, Guibin.(2015).Evaluation of the in vitro estrogenicity of emerging bisphenol analogs and their respective estrogenic contributions in municipal sewage sludge in China.CHEMOSPHERE,124,150-155. |
| MLA | Ruan, Ting,et al."Evaluation of the in vitro estrogenicity of emerging bisphenol analogs and their respective estrogenic contributions in municipal sewage sludge in China".CHEMOSPHERE 124(2015):150-155. |
入库方式： OAI收割
来源：生态环境研究中心
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