High-Throughput and Rapid Screening of Low-Mass Hazardous Compounds in Complex Samples
文献类型：期刊论文
| 作者 | Wang, Jing; Liu, Qian; Gao, Yan; Wang, Yawei; Guo, Liangqia; Jiang, Guibin |
| 刊名 | ANALYTICAL CHEMISTRY
 |
| 出版日期 | 2015-07-07 |
| 卷号 | 87期号:13页码:6931-6936 |
| 英文摘要 | Rapid screening and identification of hazardous chemicals in complex samples is of extreme importance for public safety and environmental health studies. In this work, we report a new method for high-throughput, sensitive, and rapid screening of low-mass hazardous compounds in complex media without complicated sample preparation procedures. This method is achieved based on size-selective enrichment on ordered mesoporous carbon followed by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry analysis with graphene as a matrix. The ordered mesoporous carbon CMK-8 can exclude interferences from large molecules in complex samples (e.g., human serum, urine, and environmental water samples) and efficiently enrich a wide variety of low-mass hazardous compounds. The method can work at very low concentrations down to part per trillion (ppt) levels, and it is much faster and more facile than conventional methods. It was successfully applied to rapidly screen and identify unknown toxic substances such as perfluorochemicals in human serum samples from athletes and workers. Therefore, this method not only can sensitively detect target compounds but also can identify unknown hazardous compounds in complex media. |
| 研究领域[WOS] | Chemistry, Analytical |
| WOS记录号 | WOS:000357839700075 |
| 公开日期 | 2016-03-15 |
| 源URL | [http://ir.rcees.ac.cn/handle/311016/32592]  |
| 专题 | 生态环境研究中心_环境化学与生态毒理学国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Wang, Jing,Liu, Qian,Gao, Yan,et al. High-Throughput and Rapid Screening of Low-Mass Hazardous Compounds in Complex Samples[J]. ANALYTICAL CHEMISTRY,2015,87(13):6931-6936. |
| APA | Wang, Jing,Liu, Qian,Gao, Yan,Wang, Yawei,Guo, Liangqia,&Jiang, Guibin.(2015).High-Throughput and Rapid Screening of Low-Mass Hazardous Compounds in Complex Samples.ANALYTICAL CHEMISTRY,87(13),6931-6936. |
| MLA | Wang, Jing,et al."High-Throughput and Rapid Screening of Low-Mass Hazardous Compounds in Complex Samples".ANALYTICAL CHEMISTRY 87.13(2015):6931-6936. |
入库方式： OAI收割
来源：生态环境研究中心
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