Oxidative transformation of levoflokacin by delta-MnO2: Products, pathways and toxicity assessment
文献类型：期刊论文
| 作者 | Li, Yuan; Wei, Dongbin; Du, Yuguo |
| 刊名 | CHEMOSPHERE
 |
| 出版日期 | 2015-01 |
| 卷号 | 119期号:1页码:282-288 |
| 关键词 | Levofloxacin Manganese oxide Transformation Products Pathways Toxicity |
| 英文摘要 | The characteristics of the oxidative transformation of the antibiotic levofloxacin (abbreviated as LEV) by manganese oxide were investigated. Up to 91% of LEV were removed with an equivalent of 200 units (abbreviated as equiv) of manganese oxide within a 35-day treatment period. A total of ten transformation products were identified, and five of them were newly reported. A tentative transformation pathway of LEV in the manganese oxide system involving oxidation and dealkylation was proposed. In addition, the variation in the genotoxicity and antibacterial activity along with the treatment by manganese oxide were traced using a SOS/umu assay and Escherichia coli growth inhibition assay, respectively. The results indicated that the genotoxicity significantly decreased in response to treatment with manganese oxide, while the antibacterial activity was not markedly affected until 160-equiv of delta-MnO2 were added. This study suggests that the oxidative degradation of LEV by manganese oxide can play an important role in the natural attenuation of LEV in sediment or soil matrices. The transformation reaction may be further optimized for removing quinolone antibiotics from wastewater or other environmental matrices to reduce the potential risk. (C) 2014 Elsevier Ltd. All rights reserved. |
| 研究领域[WOS] | Environmental Sciences |
| WOS记录号 | WOS:000347739600038 |
| 公开日期 | 2016-03-15 |
| 源URL | [http://ir.rcees.ac.cn/handle/311016/32637]  |
| 专题 | 生态环境研究中心_环境化学与生态毒理学国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Li, Yuan,Wei, Dongbin,Du, Yuguo. Oxidative transformation of levoflokacin by delta-MnO2: Products, pathways and toxicity assessment[J]. CHEMOSPHERE,2015,119(1):282-288. |
| APA | Li, Yuan,Wei, Dongbin,&Du, Yuguo.(2015).Oxidative transformation of levoflokacin by delta-MnO2: Products, pathways and toxicity assessment.CHEMOSPHERE,119(1),282-288. |
| MLA | Li, Yuan,et al."Oxidative transformation of levoflokacin by delta-MnO2: Products, pathways and toxicity assessment".CHEMOSPHERE 119.1(2015):282-288. |
入库方式： OAI收割
来源：生态环境研究中心
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