Total synthesis of proposed cephalosporolides H and I
文献类型：期刊论文
| 作者 | Li, Jinshan; Zhao, Chuanfang; Liu, Jun; Du, Yuguo |
| 刊名 | TETRAHEDRON
 |
| 出版日期 | 2015-06-10 |
| 卷号 | 71期号:23页码:3885-3889 |
| 关键词 | Cephalosporolide Wacker oxidation Cross-metathesis Pd-catalyst Spiroketalization |
| 英文摘要 | An efficient total synthesis toward spiroketal diastereomers of cephalosporolides H and I was achieved, respectively, taking advantage of intramolecular Wacker-type spiroketalization on the common olefin-containing dihydroxy-gamma-lactone substrate. By comparing the physical data of natural products with synthetic samples, we suggest that the reported stereochemical assignments for cephalosporolides H and I are incorrect. Our work suggests that the stereochemistry on C-6 of the core spiroketal skeleton should be revised to S from its original R assignment, and the real structures of these natural compounds should be reconsidered. (C) 2015 Elsevier Ltd. All rights reserved. |
| 研究领域[WOS] | Chemistry, Organic |
| WOS记录号 | WOS:000356125500015 |
| 公开日期 | 2016-03-15 |
| 源URL | [http://ir.rcees.ac.cn/handle/311016/32690]  |
| 专题 | 生态环境研究中心_环境化学与生态毒理学国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Li, Jinshan,Zhao, Chuanfang,Liu, Jun,et al. Total synthesis of proposed cephalosporolides H and I[J]. TETRAHEDRON,2015,71(23):3885-3889. |
| APA | Li, Jinshan,Zhao, Chuanfang,Liu, Jun,&Du, Yuguo.(2015).Total synthesis of proposed cephalosporolides H and I.TETRAHEDRON,71(23),3885-3889. |
| MLA | Li, Jinshan,et al."Total synthesis of proposed cephalosporolides H and I".TETRAHEDRON 71.23(2015):3885-3889. |
入库方式： OAI收割
来源：生态环境研究中心
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