Evaluation of residual antibacterial potency in antibiotic production wastewater using a real-time quantitative method
文献类型：期刊论文
| 作者 | Zhang, Hong; Zhang, Yu ; Yang, Min; Liu, Miaomiao
|
| 刊名 | ENVIRONMENTAL SCIENCE-PROCESSES & IMPACTS
 |
| 出版日期 | 2015 |
| 卷号 | 17期号:11页码:1923-1929 |
| 英文摘要 | While antibiotic pollution has attracted considerable attention due to its potential in promoting the dissemination of antibiotic resistance genes in the environment, the antibiotic activity of their related substances has been neglected, which may underestimate the environmental impacts of antibiotic wastewater discharge. In this study, a real-time quantitative approach was established to evaluate the residual antibacterial potency of antibiotics and related substances in antibiotic production wastewater (APW) by comparing the growth of a standard bacterial strain (Staphylococcus aureus) in tested water samples with a standard reference substance (e.g. oxytetracycline). Antibiotic equivalent quantity (EQ) was used to express antibacterial potency, which made it possible to assess the contribution of each compound to the antibiotic activity in APW. The real-time quantitative method showed better repeatability (Relative Standard Deviation, RSD 1.08%) compared with the conventional fixed growth time method (RSD 5.62-11.29%). And its quantification limits ranged from 0.20 to 24.00 mg L-1, depending on the antibiotic. We applied the developed method to analyze the residual potency of water samples from four APW treatment systems, and confirmed a significant contribution from antibiotic transformation products to potent antibacterial activity. Specifically, neospiramycin, a major transformation product of spiramycin, was found to contribute 13.15-22.89% of residual potency in spiramycin production wastewater. In addition, some unknown related substances with antimicrobial activity were indicated in the effluent. This developed approach will be effective for the management of antibacterial potency discharge from antibiotic wastewater and other waste streams. |
| 研究领域[WOS] | Chemistry, Analytical ; Environmental Sciences |
| WOS记录号 | WOS:000364146800006 |
| 公开日期 | 2016-03-15 |
| 源URL | [http://ir.rcees.ac.cn/handle/311016/32777]  |
| 专题 | 生态环境研究中心_环境水质学国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Zhang, Hong,Zhang, Yu,Yang, Min,et al. Evaluation of residual antibacterial potency in antibiotic production wastewater using a real-time quantitative method[J]. ENVIRONMENTAL SCIENCE-PROCESSES & IMPACTS,2015,17(11):1923-1929. |
| APA | Zhang, Hong,Zhang, Yu,Yang, Min,&Liu, Miaomiao.(2015).Evaluation of residual antibacterial potency in antibiotic production wastewater using a real-time quantitative method.ENVIRONMENTAL SCIENCE-PROCESSES & IMPACTS,17(11),1923-1929. |
| MLA | Zhang, Hong,et al."Evaluation of residual antibacterial potency in antibiotic production wastewater using a real-time quantitative method".ENVIRONMENTAL SCIENCE-PROCESSES & IMPACTS 17.11(2015):1923-1929. |
入库方式： OAI收割
来源：生态环境研究中心
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。