A generalized formula for inertial lift on a sphere in microchannels
文献类型:期刊论文
作者 | Liu C![]() ![]() ![]() |
刊名 | LAB ON A CHIP
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出版日期 | 2016 |
卷号 | 16期号:5页码:884-892 |
通讯作者邮箱 | guoqing.hu@imech.ac.cn |
ISSN号 | 1473-0197 |
产权排序 | [Liu, Chao; Xue, Chundong; Hu, Guoqing] Chinese Acad Sci, Inst Mech, Beijing Key Lab Engn Construct & Mechanobiol, State Key Lab Nonlinear Mech, Beijing 100190, Peoples R China; [Sun, Jiashu] Natl Ctr Nanosci & Technol, Beijing Engn Res Ctr BioNanotechnol, Beijing 100190, Peoples R China; [Sun, Jiashu] Natl Ctr Nanosci & Technol, CAS Key Lab Biol Effects Nanomat & Nanosafety, Beijing 100190, Peoples R China |
通讯作者 | Hu, GQ (reprint author), Chinese Acad Sci, Inst Mech, Beijing Key Lab Engn Construct & Mechanobiol, State Key Lab Nonlinear Mech, Beijing 100190, Peoples R China. |
中文摘要 | Inertial microfluidics has been widely used in high-throughput manipulation of particles and cells by hydrodynamic forces, without the aid of externally applied fields. The performance of inertial microfluidic devices largely relies on precise prediction of particle trajectories that are determined by inertial lift acting on particles. The only way to accurately obtain lift forces is by direct numerical simulation (DNS); however, it is burdensome when applied to practical microchannels with complex geometries. Here, we propose a fitting formula for inertial lift on a sphere drawn from DNS data obtained in straight channels. The formula consists of four terms that represent the shear-gradient-induced lift, the wall-induced lift, the slip-shear lift, and the correction of the shear-gradient-induced lift, respectively. Notably, as a function of the parameters of a local flow field, it possesses good adaptability to complex channel geometries. This generalized formula is further implemented in the Lagrangian particle tracking method to realize fast prediction of particle trajectories in two types of widely used microchannels: a long serpentine and a double spiral microchannel, demonstrating its ability to efficiently design and optimize inertial microfluidic devices. |
分类号 | 一类 |
类目[WOS] | Biochemical Research Methods ; Chemistry, Multidisciplinary ; Nanoscience & Nanotechnology |
研究领域[WOS] | Biochemistry & Molecular Biology ; Chemistry ; Science & Technology - Other Topics |
关键词[WOS] | LAGRANGIAN STATISTICS ; FLUID-MECHANICS ; MOTION ; DYNAMICS ; FIBERS ; MICROORGANISMS ; GRADIENT |
收录类别 | SCI |
原文出处 | http://dx.doi.org/10.1039/c5lc01522g |
语种 | 英语 |
WOS记录号 | WOS:000371009700009 |
源URL | [http://dspace.imech.ac.cn/handle/311007/58663] ![]() |
专题 | 力学研究所_非线性力学国家重点实验室 |
推荐引用方式 GB/T 7714 | Liu C,Xue CD,Sun JS,et al. A generalized formula for inertial lift on a sphere in microchannels[J]. LAB ON A CHIP,2016,16(5):884-892. |
APA | Liu C,Xue CD,Sun JS,&Hu GQ.(2016).A generalized formula for inertial lift on a sphere in microchannels.LAB ON A CHIP,16(5),884-892. |
MLA | Liu C,et al."A generalized formula for inertial lift on a sphere in microchannels".LAB ON A CHIP 16.5(2016):884-892. |
入库方式: OAI收割
来源:力学研究所
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