Effect of Urea on Phase Transition of Poly(N-isopropylacrylamide) and Poly(N,N-diethylacrylamide) Hydrogels: A Clue for Urea-Induced Denaturation
文献类型：期刊论文
| 作者 | Wang, Jian1,2; Liu, Biaolan1,2; Ru, Geying1; Bai, Jia1,2; Feng, Jiwen1 |
| 刊名 | MACROMOLECULES
 |
| 出版日期 | 2016-01-12 |
| 卷号 | 49期号:1页码:234-243 |
| 英文摘要 | H-1 MAS NMR spectroscopy has been applied to study the urea effect on phase transition of two similar thermosensitive polymer hydrogels: poly(N-isopropylacrylamide) (PNIPAM) and poly(N,N-diethylacrylamide) (PDEA). It is found that urea influences the phase transition of the hydrogels in opposite ways: lowering the lower critical solution temperature (LCST) of PNIPAM and hence stabilizing its globular structure, whereas raising the LCST of PDEA and destabilizing the globular structure. The self-diffusion coefficient and urea-polymer nuclear Overhauser effect (NOE) measurement reveal that urea has a stronger interaction with PNIPAM than with PDEA. Moreover, the enhanced positive water-PNIPAM NOE suggests that urea not only interacts directly with PNIPAM via hydrogen bond but also intensifies the hydrogen bonding interaction between water and PNIPAM. We suggest that different urea-polymer hydrogen bonding interaction due to the presence or absence of amide hydrogen is correlated with the distinct LCST variation of PNIPAM and PDEA. |
| WOS标题词 | Science & Technology ; Physical Sciences |
| 类目[WOS] | Polymer Science |
| 研究领域[WOS] | Polymer Science |
| 关键词[WOS] | N-ISOPROPYLACRYLAMIDE HYDROGELS ; PROTEIN DENATURATION ; NMR-SPECTROSCOPY ; AQUEOUS-SOLUTION ; THERMORESPONSIVE POLYMERS ; HYDROPHOBIC INTERACTIONS ; PREFERENTIAL ADSORPTION ; H-1-NMR SPECTROSCOPY ; COPOLYMER MICROGELS ; TISSUE SAMPLES |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000368322000027 |
| 公开日期 | 2016-03-22 |
| 源URL | [http://ir.wipm.ac.cn/handle/112942/9155]  |
| 专题 | 武汉物理与数学研究所_磁共振基础研究部 |
| 作者单位 | 1.Chinese Acad Sci, Wuhan Inst Phys & Math, Natl Ctr Magnet Resonance Wuhan, State Key Lab Magnet Resonance & Atom & Mol Phys, Wuhan 430071, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Jian,Liu, Biaolan,Ru, Geying,et al. Effect of Urea on Phase Transition of Poly(N-isopropylacrylamide) and Poly(N,N-diethylacrylamide) Hydrogels: A Clue for Urea-Induced Denaturation[J]. MACROMOLECULES,2016,49(1):234-243. |
| APA | Wang, Jian,Liu, Biaolan,Ru, Geying,Bai, Jia,&Feng, Jiwen.(2016).Effect of Urea on Phase Transition of Poly(N-isopropylacrylamide) and Poly(N,N-diethylacrylamide) Hydrogels: A Clue for Urea-Induced Denaturation.MACROMOLECULES,49(1),234-243. |
| MLA | Wang, Jian,et al."Effect of Urea on Phase Transition of Poly(N-isopropylacrylamide) and Poly(N,N-diethylacrylamide) Hydrogels: A Clue for Urea-Induced Denaturation".MACROMOLECULES 49.1(2016):234-243. |
入库方式： OAI收割
来源：武汉物理与数学研究所
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