UV-triggered thiol-disulfide exchange reaction towards tailored biodegradable hydrogels
文献类型：期刊论文
| 作者 | Wang, Linlin1; Li, Lei2; Wang, Xing1; Huang, Da1; Yang, Fei1; Shen, Hong1; Li, Zichen2; Wu, Decheng1 |
| 刊名 | POLYMER CHEMISTRY
 |
| 出版日期 | 2016 |
| 卷号 | 7期号:7页码:1429-1438 |
| 英文摘要 | We report a method of utilizing a UV-triggered thiol-disulfide exchange reaction for constructing biodegradable hydrogels with tailored properties from a water-soluble comb-like polymer of P(EMA-SS-PEG), a polyethylene glycol grafted poly(ethyl methacrylate) derivative with the disulfide linkage as the grafting point. This photochemical method provides precise spatiotemporal control over the structures and properties of disulfide-crosslinked hydrogels. By varying the irradiation time, we facilely adjust the cross-linking degree of hydrogels, thereby regulating their morphology, mechanical properties, hydrophilic properties, and swelling ratio. The photochemical method can easily fabricate macro-micro-customized patterned hydrogels, indicating its precise spatial control on the photochemical gelation process. In addition, the tailor-made biodegradable hydrogels can achieve tunable absorption and release behaviors of RB dyes, proving their potential application in controlled drug delivery. |
| 收录类别 | SCI |
| 语种 | 英语 |
| 公开日期 | 2016-05-03 |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/30109]  |
| 专题 | 化学研究所_高分子物理与化学实验室 |
| 作者单位 | 1.Chinese Acad Sci, Beijing Natl Lab Mol Sci, Inst Chem, State Key Lab Polymer Phys & Chem, Beijing 100190, Peoples R China 2.Peking Univ, Key Lab Polymer Chem & Phys, Dept Polymer Sci & Engn, BNLMS,Coll Chem & Mol Engn,Minist Educ, Beijing 100871, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Linlin,Li, Lei,Wang, Xing,et al. UV-triggered thiol-disulfide exchange reaction towards tailored biodegradable hydrogels[J]. POLYMER CHEMISTRY,2016,7(7):1429-1438. |
| APA | Wang, Linlin.,Li, Lei.,Wang, Xing.,Huang, Da.,Yang, Fei.,...&Wu, Decheng.(2016).UV-triggered thiol-disulfide exchange reaction towards tailored biodegradable hydrogels.POLYMER CHEMISTRY,7(7),1429-1438. |
| MLA | Wang, Linlin,et al."UV-triggered thiol-disulfide exchange reaction towards tailored biodegradable hydrogels".POLYMER CHEMISTRY 7.7(2016):1429-1438. |
入库方式： OAI收割
来源：化学研究所
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