Current advances in lanthanide ion (Ln(3+))-based upconversion nanomaterials for drug delivery
文献类型：期刊论文
| 作者 | Yang,Dongmei; Ma,Ping'an; Hou,Zhiyou; Cheng,Ziyong; Li,Chunxia; Lin,Jun |
| 刊名 | chemical society reviews
 |
| 出版日期 | 2015 |
| 卷号 | 44期号:6页码:1416-1448 |
| 关键词 | NEAR-INFRARED-LIGHT MESOPOROUS SILICA NANOPARTICLES RAY COMPUTED-TOMOGRAPHY CORE-SHELL NANOPARTICLES TARGETED PHOTOTHERMAL THERAPY GUIDED PHOTODYNAMIC THERAPY RESONANCE ENERGY-TRANSFER DOPED NAYF4 NANOCRYSTALS LAYER EPITAXIAL-GROWTH BIOIMAGING IN-VIVO |
| 通讯作者 | li,cx |
| 英文摘要 | lanthanide ion (ln(3+))-based upconversion nano/micromaterials that emit higher-energy visible light when excited by low-energy nir light have aroused considerable attention in the forefront of materials science and biomedical fields, which stems from their unique optical and chemical properties including minimum photodamage to living organisms, low autofluorescence, high signal-to-noise ratio and detection sensitivity, and high penetration depth in biological or environmental samples. thus, ln(3+)-based upconversion materials are rising new stars and are quickly emerging as potential candidates to revolutionize novel biomedical applications. in this review article, we mainly focus on the recent progress in various chemical syntheses of ln(3+)-based upconversion nanomaterials, with special emphasis on their application in stimuli-response controlled drug release and subsequent therapy. functional groups that are introduced into the stimuli-responsive system can respond to external triggers, such as ph, temperature, light, and even magnetic fields, which can regulate the movement of the pharmaceutical cargo and release the drug at a desired time and in a desired area. this is crucial to boost drug efficacy in cancer treatment while minimizing the side effects of cytotoxic drugs. many multifunctional (magnetic/upconversion luminescence and porous) composite materials based on ln(3+) have been designed for controlled drug delivery and multimodal bioimaging. finally, the challenges and future opportunities for ln(3+)-based upconversion materials are discussed. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000351244800007 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/64500]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Yang,Dongmei,Ma,Ping'an,Hou,Zhiyou,et al. Current advances in lanthanide ion (Ln(3+))-based upconversion nanomaterials for drug delivery[J]. chemical society reviews,2015,44(6):1416-1448. |
| APA | Yang,Dongmei,Ma,Ping'an,Hou,Zhiyou,Cheng,Ziyong,Li,Chunxia,&Lin,Jun.(2015).Current advances in lanthanide ion (Ln(3+))-based upconversion nanomaterials for drug delivery.chemical society reviews,44(6),1416-1448. |
| MLA | Yang,Dongmei,et al."Current advances in lanthanide ion (Ln(3+))-based upconversion nanomaterials for drug delivery".chemical society reviews 44.6(2015):1416-1448. |
入库方式： OAI收割
来源：长春应用化学研究所
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