Cancer biomarker detection: recent achievements and challenges
文献类型：期刊论文
| 作者 | Wu,Li,Qu,Xiaogang |
| 刊名 | chemical society reviews
 |
| 出版日期 | 2015 |
| 卷号 | 44期号:10页码:2963-2997 |
| 关键词 | CIRCULATING TUMOR-CELLS ENHANCED RAMAN-SCATTERING PROSTATE-SPECIFIC ANTIGEN ELECTROCHEMICAL IMPEDANCE SPECTROSCOPY LINKED-IMMUNOSORBENT-ASSAY SURFACE-PLASMON RESONANCE HUMAN TELOMERASE ACTIVITY REAL-TIME DETECTION HIGHLY SENSITIVE DETECTION DUPLEX-SPECIFIC NUCLEASE |
| 通讯作者 | qu,xg |
| 英文摘要 | the early detection of cancer can significantly reduce cancer mortality and saves lives. thus, a great deal of effort has been devoted to the exploration of new technologies to detect early signs of the disease. cancer biomarkers cover a broad range of biochemical entities, such as nucleic acids, proteins, sugars, small metabolites, and cytogenetic and cytokinetic parameters, as well as entire tumour cells found in the body fluid. they can be used for risk assessment, diagnosis, prognosis, and for the prediction of treatment efficacy and toxicity and recurrence. in this review, we provide an overview of recent advances in cancer biomarker detection. several representative examples using different approaches for each biomarker have been reviewed, and all these cases demonstrate that the multidisciplinary technology-based cancer diagnostics are becoming an increasingly relevant alternative to traditional techniques. in addition, we also discuss the unsolved problems and future challenges in the evaluation of cancer biomarkers. clearly, solving these hurdles requires great effort and collaboration from different communities of chemists, physicists, biologists, clinicians, material-scientists, and engineering and technical researchers. a successful outcome will result in the realization of point-of-care diagnosis and individualized treatment of cancers by non-invasive and convenient tests in the future. |
| 收录类别 | SCI |
| 语种 | 英语 |
| 公开日期 | 2016-05-03 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/64501]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Wu,Li,Qu,Xiaogang. Cancer biomarker detection: recent achievements and challenges[J]. chemical society reviews,2015,44(10):2963-2997. |
| APA | Wu,Li,Qu,Xiaogang.(2015).Cancer biomarker detection: recent achievements and challenges.chemical society reviews,44(10),2963-2997. |
| MLA | Wu,Li,Qu,Xiaogang."Cancer biomarker detection: recent achievements and challenges".chemical society reviews 44.10(2015):2963-2997. |
入库方式： OAI收割
来源：长春应用化学研究所
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