Using Plasmonic Copper Sulfide Nanocrystals as Smart Light-Driven Sterilants
文献类型：期刊论文
| 作者 | Liu,Zhen; Liu,Xianjun; Du,Yingda; Ren,Jinsong; Qu,Xiaogang |
| 刊名 | acs nano
 |
| 出版日期 | 2015 |
| 卷号 | 9期号:10页码:10335-10346 |
| 关键词 | CHEMO-PHOTOTHERMAL THERAPY UP-CONVERSION NANOPROBES IN-VIVO BIODISTRIBUTION CANCER-CELLS CONTRAST AGENTS GASTROINTESTINAL-TRACT SELENIDE NANOCRYSTALS GOLD NANORODS NANOPARTICLES STERILIZATION |
| 通讯作者 | ren,js |
| 英文摘要 | as an efficient route to control pet overpopulation and develop neutered experimental animals, male sterilization via surgical techniques, chemical injections, and antifertility vaccines has brought particular attention recently. however, these traditional ways usually induce long-term adverse reactions, immune suppression, and serious infection and pain. to overcome the above limitations, we developed a platform in the present study by using plasmonic copper sulfide nanocrystals (cu2-xs ncs) as intelligent light-driven sterilants with ideal outcomes. upon nir laser irradiation, these well-prepared cu2-xs ncs can possess nir-induced hyperthermia and generate high levels of reactive oxygen species (ros). due to the cooperation of photothermal and photodynamic effects, these nanocrystals exhibited nir-mediated toxicity toward sertoli cells both in vitro and in vivo in a mild manner. we attribute the potential mechanism of cellular injury to the apoptosis-related death and denaturation of protein in the testicles. furthermore, the possible metabolism route and long-term toxicity of these nanocrystals after testicular injection indicate their high biocompatibility. taking together, our study on the nir-induced toxicity of cu2-xs ncs provides keen insights for the usage of plasmonic nanomaterials in biomedicine. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000363915300089 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/64526]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Liu,Zhen,Liu,Xianjun,Du,Yingda,et al. Using Plasmonic Copper Sulfide Nanocrystals as Smart Light-Driven Sterilants[J]. acs nano,2015,9(10):10335-10346. |
| APA | Liu,Zhen,Liu,Xianjun,Du,Yingda,Ren,Jinsong,&Qu,Xiaogang.(2015).Using Plasmonic Copper Sulfide Nanocrystals as Smart Light-Driven Sterilants.acs nano,9(10),10335-10346. |
| MLA | Liu,Zhen,et al."Using Plasmonic Copper Sulfide Nanocrystals as Smart Light-Driven Sterilants".acs nano 9.10(2015):10335-10346. |
入库方式： OAI收割
来源：长春应用化学研究所
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