G-quadruplex enhanced fluorescence of DNA-silver nanoclusters and their application in bioimaging
文献类型：期刊论文
| 作者 | Zhu,Jinbo; Zhang,Libing; Teng,Ye; Lou,Baohua; Jia,Xiaofang; Gu,Xiaoxiao; Wang,Erkang |
| 刊名 | nanoscale
 |
| 出版日期 | 2015 |
| 卷号 | 7期号:31页码:13224-13229 |
| 关键词 | G-RICH OLIGONUCLEOTIDE METAL NANOCLUSTERS ANTI-HIV PROBE DISCOVERY APTAMERS CANCER |
| 通讯作者 | wang,ek |
| 英文摘要 | guanine proximity based fluorescence enhanced dna-templated silver nanoclusters (agncs) have been reported and applied for bioanalysis. herein, we studied the g-quadruplex enhanced fluorescence of dna-agncs and gained several significant conclusions, which will be helpful for the design of future probes. our results demonstrate that a g-quadruplex can also effectively stimulate the fluorescence potential of agncs. the major contribution of the g-quadruplex is to provide guanine bases, and its special structure has no measurable impact. the dna-templated agncs were further analysed by native polyacrylamide gel electrophoresis and the guanine proximity enhancement mechanism could be visually verified by this method. moreover, the fluorescence emission of c3a (ccca) 4 stabilized agncs was found to be easily and effectively enhanced by g-quadruplexes, such as t30695, as1411 and tba, especially as1411. benefiting from the high brightness of as1411 enhanced dna-agncs and the specific binding affinity of as1411 for nucleolin, the as1411 enhanced agncs can stain cancer cells for bioimaging. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000358732900012 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/64677]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Zhu,Jinbo,Zhang,Libing,Teng,Ye,et al. G-quadruplex enhanced fluorescence of DNA-silver nanoclusters and their application in bioimaging[J]. nanoscale,2015,7(31):13224-13229. |
| APA | Zhu,Jinbo.,Zhang,Libing.,Teng,Ye.,Lou,Baohua.,Jia,Xiaofang.,...&Wang,Erkang.(2015).G-quadruplex enhanced fluorescence of DNA-silver nanoclusters and their application in bioimaging.nanoscale,7(31),13224-13229. |
| MLA | Zhu,Jinbo,et al."G-quadruplex enhanced fluorescence of DNA-silver nanoclusters and their application in bioimaging".nanoscale 7.31(2015):13224-13229. |
入库方式： OAI收割
来源：长春应用化学研究所
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