Electrochemically and DNA-triggered cell release from ferrocene/beta-cyclodextrin and aptamer modified dual-functionalized graphene substrate
文献类型：期刊论文
| 作者 | Feng,Lingyan; Li,Wen; Ren,Jinsong; Qu,Xiaogang |
| 刊名 | nano research
 |
| 出版日期 | 2015 |
| 卷号 | 8期号:3页码:887-899 |
| 关键词 | SELF-ASSEMBLED MONOLAYERS RESPONSIVE SURFACES BETA-CYCLODEXTRIN CARBON NANOTUBES CANCER-CELLS STEM-CELLS LIVE CELLS ADHESION DIFFERENTIATION ATTACHMENT |
| 通讯作者 | qu,xg |
| 英文摘要 | here we report a dual-functionalized electrochemical substrate to trigger cancer cells release based on the supramolecular interaction between beta-cyclodextrin (beta-cd) and fc on clinical trial ii aptamer as1411 functionalized graphene platform. on one hand, the host-guest interaction can be reversible electrochemically controlled to realize cancer cells capture/release, and 1-adamantylamine binding can further amplify this surface change by competing interaction with beta-cd. on the other hand, the as1411 aptamer and its complementary dna (cdna) also can be used as a switchable anchor for cell adhesion. our work gives an example for label-free, multi-functionalized triggered cell release based on aptamer and beta-cd/graphene-modified surface and this multi-ways for cell catch-and-release on graphene modified surface also provides their potential biomedical application. |
| 收录类别 | SCI |
| 语种 | 英语 |
| 公开日期 | 2016-05-03 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/64682]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Feng,Lingyan,Li,Wen,Ren,Jinsong,et al. Electrochemically and DNA-triggered cell release from ferrocene/beta-cyclodextrin and aptamer modified dual-functionalized graphene substrate[J]. nano research,2015,8(3):887-899. |
| APA | Feng,Lingyan,Li,Wen,Ren,Jinsong,&Qu,Xiaogang.(2015).Electrochemically and DNA-triggered cell release from ferrocene/beta-cyclodextrin and aptamer modified dual-functionalized graphene substrate.nano research,8(3),887-899. |
| MLA | Feng,Lingyan,et al."Electrochemically and DNA-triggered cell release from ferrocene/beta-cyclodextrin and aptamer modified dual-functionalized graphene substrate".nano research 8.3(2015):887-899. |
入库方式： OAI收割
来源：长春应用化学研究所
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