Phase retrieval in protein crystallography
文献类型：期刊论文
| 作者 | Liu ZC(刘忠川) ; Xu R(许锐); 董宇辉;Liu, ZC; Xu, R; Dong, YH
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| 刊名 | ACTA CRYSTALLOGRAPHICA SECTION A
 |
| 出版日期 | 2012 |
| 卷号 | 68期号:2页码:256-265 |
| 关键词 | phase problem oversampling protein envelope protein crystallography |
| 英文摘要 | Solution of the phase problem is central to crystallographic structure determination. An oversampling method is proposed, based on the hybrid inputoutput algorithm (HIO) [Fienup (1982). Appl. Opt.21, 27582769], to retrieve the phases of reflections in crystallography. This method can extend low-resolution structures to higher resolution for structure determination of proteins without additional sample preparation. The method requires an envelope of the protein which divides a unit cell into the density region where the proteins are located and the non-density region occupied by solvents. After a few hundred to a few thousand iterations, the correct phases and density maps are recovered. The method has been used successfully in several cases to retrieve the phases from the experimental X-ray diffraction data and the envelopes of proteins constructed from structure files downloaded from the Protein Data Bank. It is hoped that this method will greatly facilitate the ab initio structure determination of proteins. |
| 学科主题 | Crystallography |
| 收录类别 | SCI |
| WOS记录号 | WOS:000300678400009 |
| 公开日期 | 2016-05-03 |
| 源URL | [http://ir.ihep.ac.cn/handle/311005/223914]  |
| 专题 | 高能物理研究所_多学科研究中心 |
| 推荐引用方式 GB/T 7714 | Liu ZC,Xu R,董宇辉；Liu, ZC,et al. Phase retrieval in protein crystallography[J]. ACTA CRYSTALLOGRAPHICA SECTION A,2012,68(2):256-265. |
| APA | 刘忠川,许锐,董宇辉；Liu, ZC,Xu, R,&Dong, YH.(2012).Phase retrieval in protein crystallography.ACTA CRYSTALLOGRAPHICA SECTION A,68(2),256-265. |
| MLA | 刘忠川,et al."Phase retrieval in protein crystallography".ACTA CRYSTALLOGRAPHICA SECTION A 68.2(2012):256-265. |
入库方式： OAI收割
来源：高能物理研究所
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