Controllable synthesis of Gd2O(CO3)(2)center dot H2O@silica-FITC nanoparticles with size-dependent optical and magnetic resonance imaging properties
文献类型：期刊论文
| 作者 | Zhou LJ(周亮君); Yin WY(尹文艳) ; Ren WL(任文璐); Zhou, LJ; Yin, WY; Ren, WL; Gu, ZJ; Li, W; Jin, S; Yan, L
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| 刊名 | NEW JOURNAL OF CHEMISTRY
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| 出版日期 | 2012 |
| 卷号 | 36期号:12页码:2599-2606 |
| 英文摘要 | Gadolinium carbonate (Gd2O(CO3)(2)center dot H2O) nanoparticles (NPs) with different diameters (from 280 nm to 10 nm) were obtained through a simple hydrothermal process by adding different volumes of glycerol. These Gd2O(CO3)(2)center dot H2O NPs were further coated with a thin layer of silica containing fluorescent dye (fluorescein isothiocyanate, FITC), and the possibility of using these NPs for optical imaging was demonstrated. In addition, due to the presence of Gd3+ ions on the surface of the NPs, magnetic resonance imaging (MRI) of Gd2O(CO3)(2)center dot H2O NPs with different diameters was also reported in detail. Considering the effect of NPs' size on their biocompatibility and MRI properties, our research results indicated that the Gd2O(CO3)(2)center dot H2O NPs of 50 nm showed the highest cytotoxicity and the maximum uptake by cells, and the MRI properties of Gd2O(CO3)(2)center dot H2O@silica-FITC NPs are also size-dependent. Therefore, these NPs exhibit bifunctionality for both optical imaging and MRI, making them potentially applicable in the biomedical field. |
| 学科主题 | Chemistry |
| 收录类别 | SCI |
| WOS记录号 | WOS:000311971400024 |
| 公开日期 | 2016-05-03 |
| 源URL | [http://ir.ihep.ac.cn/handle/311005/224208]  |
| 专题 | 高能物理研究所_多学科研究中心 |
| 推荐引用方式 GB/T 7714 | Zhou LJ,Yin WY,Ren WL,et al. Controllable synthesis of Gd2O(CO3)(2)center dot H2O@silica-FITC nanoparticles with size-dependent optical and magnetic resonance imaging properties[J]. NEW JOURNAL OF CHEMISTRY,2012,36(12):2599-2606. |
| APA | 周亮君.,尹文艳.,任文璐.,Zhou, LJ.,Yin, WY.,...&赵宇亮.(2012).Controllable synthesis of Gd2O(CO3)(2)center dot H2O@silica-FITC nanoparticles with size-dependent optical and magnetic resonance imaging properties.NEW JOURNAL OF CHEMISTRY,36(12),2599-2606. |
| MLA | 周亮君,et al."Controllable synthesis of Gd2O(CO3)(2)center dot H2O@silica-FITC nanoparticles with size-dependent optical and magnetic resonance imaging properties".NEW JOURNAL OF CHEMISTRY 36.12(2012):2599-2606. |
入库方式： OAI收割
来源：高能物理研究所
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