Surface Functionalized Gold Nanorods: Tracking and Observing Live Cell via Three Optical Signals
文献类型：期刊论文
| 作者 | Qiu, XZ; Wang YL(王亚玲) ; Cui YY(崔艳艳); Wang, YL; Cui, YY; Sun, ZP; Liu, R; Huang, WH; Zhao, F; Zu, Y
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| 刊名 | JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
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| 出版日期 | 2012 |
| 卷号 | 12期号:9页码:6893-6899 |
| 关键词 | Gold Nanorods Multi-Signal Cell-Penetrating Peptide Raman Fluorescent MGITC Dark-Field |
| 英文摘要 | Surface functionalized gold nanorods (GNRs) with three optical signals and the ability to track and observe live cells was investigated. The Cetyltrimethyl Ammonium Bromide (CTAB) was used as the shape-directing agent to develop GNRs with uniform size and aspect ratio. The as-synthesized GNRs can strongly enhance the Raman signal of the attached MGITC on the GNRs. Polyethylene glycol (SH-PEG-COOH) and SH-PEG-FITC were attached with GNRs through ligand exchange with CTAB. They can stabilize the GNRs, reduce the cytotoxicity and provide fluorescence signal. A cell-penetrating peptide was covalently conjugated with SH-PEG-COOH to assist the GNRs to enter living cell. After cultured with the MCF-7 cells, the surfaced functionalized Au nanorods can enter the MCF-7 cells and be tracking with enhanced MGITC Raman signal, FITC fluorescence, and Rayleigh scatter signal. |
| 学科主题 | Chemistry; Science & Technology - Other Topics; Materials Science; Physics |
| 收录类别 | SCI |
| WOS记录号 | WOS:000308856200004 |
| 公开日期 | 2016-05-03 |
| 源URL | [http://ir.ihep.ac.cn/handle/311005/224284]  |
| 专题 | 高能物理研究所_多学科研究中心 |
| 推荐引用方式 GB/T 7714 | Qiu, XZ,Wang YL,Cui YY,et al. Surface Functionalized Gold Nanorods: Tracking and Observing Live Cell via Three Optical Signals[J]. JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY,2012,12(9):6893-6899. |
| APA | Qiu, XZ.,王亚玲.,崔艳艳.,Wang, YL.,Cui, YY.,...&高学云.(2012).Surface Functionalized Gold Nanorods: Tracking and Observing Live Cell via Three Optical Signals.JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY,12(9),6893-6899. |
| MLA | Qiu, XZ,et al."Surface Functionalized Gold Nanorods: Tracking and Observing Live Cell via Three Optical Signals".JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY 12.9(2012):6893-6899. |
入库方式： OAI收割
来源：高能物理研究所
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