Embedded Carbon Nanotubes Nanoparticles in Plasma Membrane Induce Cellular Calcium Outflow Imbalancing
文献类型：期刊论文
| 作者 | Wang JY(汪景怡); 刘茹;Wang, JY; Liu, R; Su, YM; Li, W |
| 刊名 | JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
 |
| 出版日期 | 2014 |
| 卷号 | 14期号:6页码:4058-4065 |
| 关键词 | Carbon Nanotubes Nanoparticles Cellular Membrane Calcium |
| 英文摘要 | In this report, embedded single-wall carbon nanotubes (SWCNTs) nanoparticles in plasma membrane inducing cellular calcium outflow imbalancing are disclosed. Compared ssDNA-SWCNTs with polystyrene (PS) nanoparticles, we analyzed the cytotoxicity of these nanoparticles and the effect of these nanoparticles on intracellular Ca2+ ion levels by depletion of Ca2+ from the endoplasmic reticulum (ER) evoked by Thapsigargin (Tg) in SKN-SH cells. The results had shown that ssDNA-SWCNTs and PS nanoparticles have no cytotoxicity on SKN-SH cells. However, contrary to PS nanoparticles, cellular Ca2+ ion outflow imbalancing was investigated in SKN-SH cells after pretreated with ssDNA-SWCNTs induced by Tg, which could be proposed mainly due to the interaction of embedded ssDNA-SWCNTs with cellular membrane. |
| 学科主题 | Chemistry; Science & Technology - Other Topics; Materials Science; Physics |
| 收录类别 | SCI |
| WOS记录号 | WOS:000332339500008 |
| 公开日期 | 2016-05-03 |
| 源URL | [http://ir.ihep.ac.cn/handle/311005/225125]  |
| 专题 | 中国科学院高能物理研究所 |
| 推荐引用方式 GB/T 7714 | Wang JY,刘茹；Wang, JY,Liu, R,et al. Embedded Carbon Nanotubes Nanoparticles in Plasma Membrane Induce Cellular Calcium Outflow Imbalancing[J]. JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY,2014,14(6):4058-4065. |
| APA | 汪景怡,刘茹；Wang, JY,Liu, R,Su, YM,&Li, W.(2014).Embedded Carbon Nanotubes Nanoparticles in Plasma Membrane Induce Cellular Calcium Outflow Imbalancing.JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY,14(6),4058-4065. |
| MLA | 汪景怡,et al."Embedded Carbon Nanotubes Nanoparticles in Plasma Membrane Induce Cellular Calcium Outflow Imbalancing".JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY 14.6(2014):4058-4065. |
入库方式： OAI收割
来源：高能物理研究所
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