3D local structure around Zn in Kti11p as a representative Zn-(Cys)4 motif as obtained by MXAN
文献类型：期刊论文
| 作者 | Yu MJ(于梅娟) ; Yang FF(杨飞飞); Chu WS(储旺盛); Zhao HF(赵海峰); Gao B(高斌); Wu ZY(吴自玉); Yu, MJ; Yang, FF; Chu, WS; Wang, Y
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| 刊名 | BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
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| 出版日期 | 2008 |
| 卷号 | 374期号:1页码:#REF! |
| 关键词 | zinc motif Kti11p EXAFS XANES fingerprints MXAN |
| 通讯作者 | Chu, WS (reprint author), Chinese Acad Sci, Inst High Energy Phys, Beijing Synchrotron Radiat Facil, 19B YuquanLu, Beijing 100049, Peoples R China. |
| 英文摘要 | Zinc is an important component of many proteins that play key roles in transcription, translation, and catalysis. Kti11p, DESR1, both belonging to a protein family characterized by a CSL zinc finger domain, and the co-catalytic zinc-protein PML containing a Zn(2+) binding domain called RING or C(3)HC(4) finger are all structurally determined by NMR although the zinc sites are silent to this spectroscopical method. The comparison of X-ray absorption near-edge spectroscopy (XANES) data for the three proteins demonstrates that fingerprints effect is a reliable method for a primary characterization of ligand species. Ab initio full MS Calculations performed by MAN are applied to obtain chemical and stereo structural information around the Zn ion in Kti11p. For the first time this high-spatial resolution technique confirms the formation of a stable Zn tetrahedral configuration with four sulfur ligands, and returns extremely accurate bond angle information between ligands. (C) 2008 Elsevier Inc. All rights reserved. |
| 学科主题 | Biochemistry & Molecular Biology; Biophysics |
| 类目[WOS] | Biochemistry & Molecular Biology ; Biophysics |
| 收录类别 | SCI |
| WOS记录号 | WOS:000258798700006 |
| 公开日期 | 2016-05-03 |
| 源URL | [http://ir.ihep.ac.cn/handle/311005/225596]  |
| 专题 | 高能物理研究所_多学科研究中心 |
| 推荐引用方式 GB/T 7714 | Yu MJ,Yang FF,Chu WS,et al. 3D local structure around Zn in Kti11p as a representative Zn-(Cys)4 motif as obtained by MXAN[J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,2008,374(1):#REF!. |
| APA | 于梅娟.,杨飞飞.,储旺盛.,赵海峰.,高斌.,...&Wu, ZY.(2008).3D local structure around Zn in Kti11p as a representative Zn-(Cys)4 motif as obtained by MXAN.BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,374(1),#REF!. |
| MLA | 于梅娟,et al."3D local structure around Zn in Kti11p as a representative Zn-(Cys)4 motif as obtained by MXAN".BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 374.1(2008):#REF!. |
入库方式： OAI收割
来源：高能物理研究所
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