Novel carbon nanohybrids as highly efficient magnetic resonance imaging contrast agents
文献类型：期刊论文
| 作者 | Cui RL(崔荣丽) ; Li J(李娟); Huang H(黄换); Zhang MY(张铭倚); Guo XH(郭喜红); Li M(李敏); Dong JQ(董金泉); Sun BY(孙宝云); Xing GM(邢更妹); Cui, RL
|
| 刊名 | NANO RESEARCH
 |
| 出版日期 | 2015 |
| 卷号 | 8期号:4页码:1259-1268 |
| 关键词 | graphene oxide metallofullerene magnetic resonance imaging (MRI) nanohybrids |
| 通讯作者 | 孙宝云 ; 邢更妹 |
| 英文摘要 | Novel carbon nanohybrids based on unmodified metallofullerenes have been successfully fabricated for use as a new magnetic resonance imaging (MRI) contrast agent. The nanohybrids showed higher R (1) relaxivity and better brightening effect than Gd@C-82(OH) (X) , in T (1)-weighted MR images in vivo. This is a result of the proton relaxivity from the original gadofullerenes, which retained a perfect carbon cage structure and so might completely avoid the release of Gd3+ ions. A "secondary spin-electron transfer" relaxation mechanism was proposed to explain how the encaged Gd3+ ions of carbon nanohybrids interact with the surrounding water molecules. This approach opens new opportunities for developing highly efficient and low toxicity MRI contrast agents. |
| 学科主题 | Chemistry; Science & Technology - Other Topics; Materials Science; Physics |
| 类目[WOS] | Chemistry, Physical ; Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary ; Physics, Applied |
| 收录类别 | SCI ; CA |
| WOS记录号 | WOS:000353807500020 |
| 公开日期 | 2016-05-03 |
| 源URL | [http://ir.ihep.ac.cn/handle/311005/228294]  |
| 专题 | 高能物理研究所_多学科研究中心 |
| 推荐引用方式 GB/T 7714 | Cui RL,Li J,Huang H,et al. Novel carbon nanohybrids as highly efficient magnetic resonance imaging contrast agents[J]. NANO RESEARCH,2015,8(4):1259-1268. |
| APA | 崔荣丽.,李娟.,黄换.,张铭倚.,郭喜红.,...&Xing, GM.(2015).Novel carbon nanohybrids as highly efficient magnetic resonance imaging contrast agents.NANO RESEARCH,8(4),1259-1268. |
| MLA | 崔荣丽,et al."Novel carbon nanohybrids as highly efficient magnetic resonance imaging contrast agents".NANO RESEARCH 8.4(2015):1259-1268. |
入库方式： OAI收割
来源：高能物理研究所
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