Altered regional homogeneity in post-traumatic stress disorder: a restingstate functional magnetic resonance imaging study
文献类型：期刊论文
| 作者 | Yin, Y; Jin, CF; Eyler, LT; Jin, H; Hu, XL; Duan, L; Zheng, HR; Feng, B; Huang, XY; Shan, BC |
| 刊名 | NEUROSCIENCE BULLETIN
 |
| 出版日期 | 2012 |
| 卷号 | 28期号:5页码:541-549 |
| 关键词 | functional magnetic resonance imaging post-traumatic stress disorder regional homogeneity resting-state |
| 英文摘要 | Little is known about the brain systems that contribute to vulnerability to post-traumatic stress disorder (PTSD). Comparison of the resting-state patterns of intrinsic functional synchronization, as measured by functional magnetic resonance imaging (fMRI), between groups with and without PTSD following a traumatic event can help identify the neural mechanisms of the disorder and targets for intervention. Fifty-four PTSD patients and 72 matched traumatized subjects who experienced the 2008 Sichuan earthquake were imaged with blood oxygen level-dependent (BOLD) fMRI and analyzed using the measure of regional homogeneity (ReHo) during the resting state. PTSD patients presented enhanced ReHo in the left inferior parietal lobule and right superior frontal gyrus, and reduced ReHo in the right middle temporal gyrus and lingual gyrus, relative to traumatized individuals without PTSD. Our findings showed that abnormal brain activity exists under resting conditions in PTSD patients who had been exposed to a major earthquake. Alterations in the local functional connectivity of cortical regions are likely to contribute to the neural mechanisms underlying PTSD. |
| 学科主题 | Neurosciences & Neurology |
| 收录类别 | SCI |
| WOS记录号 | WOS:000309357800009 |
| 公开日期 | 2016-05-03 |
| 源URL | [http://ir.ihep.ac.cn/handle/311005/224010]  |
| 专题 | 高能物理研究所_核技术应用研究中心 |
| 推荐引用方式 GB/T 7714 | Yin, Y,Jin, CF,Eyler, LT,et al. Altered regional homogeneity in post-traumatic stress disorder: a restingstate functional magnetic resonance imaging study[J]. NEUROSCIENCE BULLETIN,2012,28(5):541-549. |
| APA | Yin, Y.,Jin, CF.,Eyler, LT.,Jin, H.,Hu, XL.,...&Li, LJ；单保慈.(2012).Altered regional homogeneity in post-traumatic stress disorder: a restingstate functional magnetic resonance imaging study.NEUROSCIENCE BULLETIN,28(5),541-549. |
| MLA | Yin, Y,et al."Altered regional homogeneity in post-traumatic stress disorder: a restingstate functional magnetic resonance imaging study".NEUROSCIENCE BULLETIN 28.5(2012):541-549. |
入库方式： OAI收割
来源：高能物理研究所
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