Performance Evaluation and Initial Clinical Test of the Positron Emission Mammography System (PEMi)
文献类型：期刊论文
| 作者 | Li L(李琳) ; Gu XY(顾笑悦); Li DW(李道武); Huang XC(黄先超); Chai P(柴培); Feng BT(丰宝桐); Wang PL(王培林); Yuan MK(贠明凯); Zhang ZM(章志明); Yin PF(尹鹏飞)
|
| 刊名 | IEEE TRANSACTIONS ON NUCLEAR SCIENCE
 |
| 出版日期 | 2015 |
| 卷号 | 62期号:5页码:2048-2056 |
| 关键词 | Biomedical imaging breast cancer gamma-ray detectors positron emission mammography (PEM) positron emission tomography (PET) |
| 通讯作者 | 李琳 |
| 英文摘要 | A new polygon positron emission mammography imaging system (PEMi) was developed in 2009 by the Institute of High Energy Physics, Chinese Academy of Sciences. PEMi is constructed in a polygon structure with lutetium yttrium orthosilicate crystal arrays mounted on a position-sensitive photomultiplier. The system consists of 64 blocks and each block is arranged in crystal arrays with a pixel size of 1.9 x 1.9 x 15 mm. The diameter of the detector ring is 166 mm, and the axial length is 128 mm. The transaxial field of view of PEMi is 110 mm. The goal of the initial study was to test PEMi's performance and the clinical imaging ability with a small group of selected subjects. The detectors have a measured intrinsic spatial resolution averaging 1.67 mm. The axial and tangential resolution remained under 2.5-mm full width at half maximum within the central 5-cm diameter of the field of view. The hot rods with a diameter of 1.7 mm can be clearly identified, and the structure of the region containing 1.35-mm diameter rods can also be observed. Using a 6-ns coincidence timing window and a 360 similar to 660-keV energy window, the peak sensitivity of the tomograph is 6.88%. The noise-equivalent count rate peak is 110 766 cps for a breast-like cylindrical phantom of 100 mm in diameter at an activity concentration of 0.03 MBq/cc. The recovery coefficients ranged from 0.21 to 0.85 for rods between 1 mm and 5 mm in the image-quality phantom. The reconstructed image resolution achieved an improvement compared with whole-body positron emission tomography (PET), which might reduce the lower threshold on detectable lesion size. Example patient images demonstrate that PEMi is clinically feasible. And more detailed structure information was obtained with PEMi than with the whole-body PET imaging. |
| 学科主题 | Engineering; Nuclear Science & Technology |
| 类目[WOS] | Engineering, Electrical & Electronic ; Nuclear Science & Technology |
| 收录类别 | SCI |
| WOS记录号 | WOS:000363242200017 |
| 公开日期 | 2016-05-03 |
| 源URL | [http://ir.ihep.ac.cn/handle/311005/229009]  |
| 专题 | 高能物理研究所_核技术应用研究中心 中国科学院高能物理研究所_中国散裂中子源 |
| 推荐引用方式 GB/T 7714 | Li L,Gu XY,Li DW,et al. Performance Evaluation and Initial Clinical Test of the Positron Emission Mammography System (PEMi)[J]. IEEE TRANSACTIONS ON NUCLEAR SCIENCE,2015,62(5):2048-2056. |
| APA | 李琳.,顾笑悦.,李道武.,黄先超.,柴培.,...&W. G. Xu and L. Wei.(2015).Performance Evaluation and Initial Clinical Test of the Positron Emission Mammography System (PEMi).IEEE TRANSACTIONS ON NUCLEAR SCIENCE,62(5),2048-2056. |
| MLA | 李琳,et al."Performance Evaluation and Initial Clinical Test of the Positron Emission Mammography System (PEMi)".IEEE TRANSACTIONS ON NUCLEAR SCIENCE 62.5(2015):2048-2056. |
入库方式： OAI收割
来源：高能物理研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。