Anatomical model-based finite element analysis of the combined cryosurgical and hyperthermic ablation for knee bone tumor
文献类型：期刊论文
| 作者 | He, ZZ; Xue, X; 肖剑;Xiao, J; Liu, J |
| 刊名 | COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE
 |
| 出版日期 | 2013 |
| 卷号 | 112期号:3页码:356-366 |
| 关键词 | Cryosurgery Hyperthermia Alternate freezing-heating Knee bone tumor Anatomical CAD model |
| 英文摘要 | This paper is aimed at investigating the capacity of using combined cryosurgical and hyperthermic modality for treating knee bone tumor with complex shape. An anatomical model for human knee was constructed and a three-dimensional (3D) finite element analysis was developed to determine temperature distribution of the tissues subject to single freezing (SF), single heating (SH) and alternate freezing-heating (AFH), respectively. The heat fluxes of the probes wall and the ablation volume are particularly tracked to comparatively evaluate the ablation ability of different probe configurations with varied diameter, number and active working length. As example, an effective conformal treatment strategy via one time's insertion while cyclic freezing-heating using multiple probes is designed for a predefined knee bone tumor ablation. Both SF and SH could create large enough ablation volume, while it is hard for them to perform a conformal treatment on irregular and slender knee tumor. As an alternative, AFH could form a flexible and controlled shape and volume of the ablation by changing the size and number of the probes and adjusting their insertion depth. In addition, a thermal protection method is considered to reduce cryoinjury of the health tissue. (C) 2013 Elsevier Ireland Ltd. All rights reserved. |
| 学科主题 | Computer Science; Engineering; Medical Informatics |
| 收录类别 | SCI |
| WOS记录号 | WOS:000325750100005 |
| 公开日期 | 2016-05-03 |
| 源URL | [http://ir.ihep.ac.cn/handle/311005/223950]  |
| 专题 | 高能物理研究所_加速器中心 |
| 推荐引用方式 GB/T 7714 | He, ZZ,Xue, X,肖剑；Xiao, J,et al. Anatomical model-based finite element analysis of the combined cryosurgical and hyperthermic ablation for knee bone tumor[J]. COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE,2013,112(3):356-366. |
| APA | He, ZZ,Xue, X,肖剑；Xiao, J,&Liu, J.(2013).Anatomical model-based finite element analysis of the combined cryosurgical and hyperthermic ablation for knee bone tumor.COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE,112(3),356-366. |
| MLA | He, ZZ,et al."Anatomical model-based finite element analysis of the combined cryosurgical and hyperthermic ablation for knee bone tumor".COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE 112.3(2013):356-366. |
入库方式： OAI收割
来源：高能物理研究所
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