Translocation of inhaled TiO2 nanoparticles along olfactory nervous system to brain studied by synchrotron radiation X-ray fluorescence
文献类型：期刊论文
| 作者 | Wang JX(王江雪); Chen CY(陈春英); Sun J(孙瑾); Yu HW(喻宏伟); Li YF(李玉锋) ; Li B(李柏); Xing L(邢丽); Huang YY(黄宇营); He W(何伟); Gao YX(高愈希)
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| 刊名 | HIGH ENERGY PHYSICS AND NUCLEAR PHYSICS-CHINESE EDITION
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| 出版日期 | 2005 |
| 卷号 | 29页码:#REF! |
| 关键词 | SRXRF nano-TiO2 mouse brain elemental distribution nanosafety |
| 其他题名 | 用SRXRF研究纳米 TiO2颗粒沿小鼠嗅觉神经系统的迁移 |
| 通讯作者 | Wang, JX (reprint author), Chinese Acad Sci, Inst High Energy Phys, Beijing 100049, Peoples R China. |
| 英文摘要 | Nanosized TiO2 is widely used for cleaning air, antibacterial and decomposing organic in wastewater for its highly photocatalytic function. TiO2 inhalation via respiratory tracts is the most common route of its exposure in industry and environment. After inhalation by human or rodents, TiO2 can induce inflammation and pulmonary lesions, which was reported to even cause lung cancer by long-term exposure. In this paper, Synchrotron Radiation X-ray Fluorescence was employed to investigate the distribution of TiO2 in the olfactory bulb and brain of mice after inhalation of TiO2 particles suspension. The results showed that TiO2 could enter the olfactory nerve layer (ON), granular cell layer of olfactory bulb (Gro), and olfactory ventricle (OV) and further the hippocampus, thalamus, and CA3 area of the brain through the olfactory nervous system. The distribution area of microsized TiO2 was wider than that of nanosized TiO2. |
| 学科主题 | Physics |
| 类目[WOS] | Physics, Nuclear ; Physics, Particles & Fields |
| 收录类别 | SCI |
| WOS记录号 | WOS:000234206900020 |
| 公开日期 | 2016-05-03 |
| 源URL | [http://ir.ihep.ac.cn/handle/311005/225980]  |
| 专题 | 高能物理研究所_院士 高能物理研究所_实验物理中心 高能物理研究所_多学科研究中心 |
| 推荐引用方式 GB/T 7714 | Wang JX,Chen CY,Sun J,et al. Translocation of inhaled TiO2 nanoparticles along olfactory nervous system to brain studied by synchrotron radiation X-ray fluorescence[J]. HIGH ENERGY PHYSICS AND NUCLEAR PHYSICS-CHINESE EDITION,2005,29:#REF!. |
| APA | 王江雪.,陈春英.,孙瑾.,喻宏伟.,李玉锋.,...&Zhao, YL.(2005).Translocation of inhaled TiO2 nanoparticles along olfactory nervous system to brain studied by synchrotron radiation X-ray fluorescence.HIGH ENERGY PHYSICS AND NUCLEAR PHYSICS-CHINESE EDITION,29,#REF!. |
| MLA | 王江雪,et al."Translocation of inhaled TiO2 nanoparticles along olfactory nervous system to brain studied by synchrotron radiation X-ray fluorescence".HIGH ENERGY PHYSICS AND NUCLEAR PHYSICS-CHINESE EDITION 29(2005):#REF!. |
入库方式： OAI收割
来源：高能物理研究所
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