Variations of elemental distribution in brain regions of neonatal rats at different iodine intakes
文献类型：期刊论文
| 作者 | Zhang F(张帆) ; Liu NQ(刘年庆); Xu Q(徐清); Wang XF(王学峰); Huang YY(黄宇营); He W(何伟); Chai ZF(柴之芳); Zhang, F; Liu, NQ; Zhao, XQ
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| 刊名 | BIOLOGICAL TRACE ELEMENT RESEARCH
 |
| 出版日期 | 2002 |
| 卷号 | 90期号:1-3页码:#REF! |
| 关键词 | iodine deficiency trace element SRXRF cerebral cortex hippocampus |
| 通讯作者 | Zhang, F (reprint author), Acad Sinica, Inst High Energy Phys, Lab Nucl Analyt Tech, Beijing 100039, Peoples R China. |
| 英文摘要 | Iodine deficiency (ID) can result in irreversible damage to the brain during the fetal and neonatal stages. As the active center of many enzymes, trace elements play essential roles in brain function. In this work, the relative contents and distributions of elements (Cl, Br, Fe, Cu, and Zn) in two important brain regions, the cerebral cortex and hippocampus, of the iodine-deficient model rats were determined by the synchrotron radiation X-ray fluorescence (SRXRF) method. Meanwhile, the ID rats were supplemented with adequate and excessive iodine, respectively. The results indicated that the distributions of trace elements could be influenced by the different iodine intakes in the stage of brain development. In contrast to the control group, the contents of Cl, Br, and Zn in two brain regions showed a significant increase in the ID group; however, both Fe and Cu decreased in the cerebral cortex and increased in the hippocmapus in the ID group. In addition, only slight changes of elemental contents in brain were found between the adequate and excessive iodine-supplemented rats. |
| 学科主题 | Biochemistry & Molecular Biology; Endocrinology & Metabolism |
| 类目[WOS] | Biochemistry & Molecular Biology ; Endocrinology & Metabolism |
| 收录类别 | SCI |
| WOS记录号 | WOS:000180413500018 |
| 公开日期 | 2016-05-03 |
| 源URL | [http://ir.ihep.ac.cn/handle/311005/227066]  |
| 专题 | 高能物理研究所_院士 |
| 推荐引用方式 GB/T 7714 | Zhang F,Liu NQ,Xu Q,et al. Variations of elemental distribution in brain regions of neonatal rats at different iodine intakes[J]. BIOLOGICAL TRACE ELEMENT RESEARCH,2002,90(1-3):#REF!. |
| APA | 张帆.,刘年庆.,徐清.,王学峰.,黄宇营.,...&Chai, ZF.(2002).Variations of elemental distribution in brain regions of neonatal rats at different iodine intakes.BIOLOGICAL TRACE ELEMENT RESEARCH,90(1-3),#REF!. |
| MLA | 张帆,et al."Variations of elemental distribution in brain regions of neonatal rats at different iodine intakes".BIOLOGICAL TRACE ELEMENT RESEARCH 90.1-3(2002):#REF!. |
入库方式： OAI收割
来源：高能物理研究所
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