热门
Three-dimensional graphene foam as a biocompatible and conductive scaffold for neural stem cells
文献类型：期刊论文
| 作者 | Cheng, GS（程国胜） ; Liu, LW（刘立伟）; Song, Q（宋琴）; Dai, JW（戴建武）
|
| 刊名 | SCIENTIFIC REPORTS
 |
| 出版日期 | 2013-03 |
| 卷号 | 3期号:0 |
| 通讯作者 | Dai, JW（戴建武） |
| 英文摘要 | Neural stem cell (NSC) based therapy provides a promising approach for neural regeneration. For the success of NSC clinical application, a scaffold is required to provide three-dimensional (3D) cell growth microenvironments and appropriate synergistic cell guidance cues. Here, we report the first utilization of graphene foam, a 3D porous structure, as a novel scaffold for NSCs in vitro. It was found that three-dimensional graphene foams (3D-GFs) can not only support NSC growth, but also keep cell at an active proliferation state with upregulation of Ki67 expression than that of two-dimensional graphene films. Meanwhile, phenotypic analysis indicated that 3D-GFs can enhance the NSC differentiation towards astrocytes and especially neurons. Furthermore, a good electrical coupling of 3D-GFs with differentiated NSCs for efficient electrical stimulation was observed. Our findings implicate 3D-GFs could offer a powerful platform for NSC research, neural tissue engineering and neural prostheses. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000316984600002 |
| 公开日期 | 2014-01-15 |
| 源URL | [http://ir.sinano.ac.cn/handle/332007/1372]  |
| 专题 | 苏州纳米技术与纳米仿生研究所_纳米生物医学与安全研究部_戴建武团队 苏州纳米技术与纳米仿生研究所_纳米器件及相关材料研究部_刘立伟团队 苏州纳米技术与纳米仿生研究所_纳米生物医学与安全研究部_程国胜团队 |
| 通讯作者 | Dai, JW（戴建武） |
| 推荐引用方式 GB/T 7714 | Cheng, GS,Liu, LW,Song, Q,et al. Three-dimensional graphene foam as a biocompatible and conductive scaffold for neural stem cells[J]. SCIENTIFIC REPORTS,2013,3(0). |
| APA | Cheng, GS,Liu, LW,Song, Q,&Dai, JW.(2013).Three-dimensional graphene foam as a biocompatible and conductive scaffold for neural stem cells.SCIENTIFIC REPORTS,3(0). |
| MLA | Cheng, GS,et al."Three-dimensional graphene foam as a biocompatible and conductive scaffold for neural stem cells".SCIENTIFIC REPORTS 3.0(2013). |
入库方式： OAI收割
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。