Synthesis and Biocompatibility of Amphiphilic Graphene Oxide
文献类型：期刊论文
| 作者 | Cheng, GS(程国胜) ; Song, Q(宋琴)
|
| 刊名 | CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE
 |
| 出版日期 | 2013-01 |
| 卷号 | 5期号:3页码:949-957 |
| 关键词 | Amphiphilic graphene oxide Biocompatibility TWEEN 80 Hexamethylene diisocyanate |
| 通讯作者 | Cheng, GS(程国胜) |
| 英文摘要 | Amphiphilic functionalization of graphene oxide(GO) is of the essence for its biomedical applications. TWEEN 80-grafted GO was synthesized by a two-step approach. In step 1, GO surface was activated with hexamethylene diisocyanate(HMDI) through a reaction between GO carboxyl or hydroxyl groups and isocyanate. HMDI-activated GO was then grafted by TWEEN 80 in step 2, resulting in amphiphilic GO nanosheets. The fabricated TWEEN 80-grafted GO exhibited excellent dispersibility in various solvents, such as water, chloroform and n-hexane. Furthermore, PC12 and HeLa cells were cultured on TWEEN 80-grafted GO film to assess its cytotoxicity. Cell morphology analysis and cell viability assay(Calcein AM &EthD-1 staining and MTT assay) indicated that the as-synthesized amphiphilic GO had good biocompatibility. |
| 收录类别 | SCI ; EI |
| 语种 | 英语 |
| WOS记录号 | WOS:000317085300007 |
| 公开日期 | 2014-01-15 |
| 源URL | [http://ir.sinano.ac.cn/handle/332007/1387]  |
| 专题 | 苏州纳米技术与纳米仿生研究所_纳米生物医学与安全研究部_程国胜团队 |
| 通讯作者 | Cheng, GS(程国胜) |
| 推荐引用方式 GB/T 7714 | Cheng, GS,Song, Q. Synthesis and Biocompatibility of Amphiphilic Graphene Oxide[J]. CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE,2013,5(3):949-957. |
| APA | Cheng, GS,&Song, Q.(2013).Synthesis and Biocompatibility of Amphiphilic Graphene Oxide.CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE,5(3),949-957. |
| MLA | Cheng, GS,et al."Synthesis and Biocompatibility of Amphiphilic Graphene Oxide".CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE 5.3(2013):949-957. |
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