Quantification of Zn(II) using a label-free sensor based on graphene oxide and G-quadruplex
文献类型：期刊论文
| 作者 | Guo, YH（郭亚辉）; Sun, Y（孙艳）; Shen, XQ（申小强）; Chen, X（陈星）; Yao, WR; Xie, YF; Hu, JM; Pei, RJ(裴仁军) |
| 刊名 | ANALYTICAL METHODS
 |
| 出版日期 | 2015 |
| 卷号 | 7期号:22页码:4 |
| 通讯作者 | Hu, JM |
| 英文摘要 | By employing two-dimensional and water-soluble graphene oxide (GO), a turn-on sensor was developed for the label-free detection of Zn2+ based on Zn2+-induced G-quadruplex (G4) formation. Indicated using the G4-binding ligand thiazole orange (TO), the enhanced fluorescent signal could be generated only when the guanine-rich DNA was excluded from the surface of GO due to the formation of a G4 induced by Zn2+. The results have shown that the method can be utilized for the detection of Zn2+ in a linear range from 0-30 mu M with a detection limit of 0.71 mu M. The real sample testing conducted in serum samples demonstrated its practical potential in biological analysis. |
| 收录类别 | SCI |
| 语种 | 英语 |
| 源URL | [http://ir.sinano.ac.cn/handle/332007/3450]  |
| 专题 | 苏州纳米技术与纳米仿生研究所_纳米生物医学与安全研究部_裴仁军团队 |
| 推荐引用方式 GB/T 7714 | Guo, YH,Sun, Y,Shen, XQ,et al. Quantification of Zn(II) using a label-free sensor based on graphene oxide and G-quadruplex[J]. ANALYTICAL METHODS,2015,7(22):4. |
| APA | Guo, YH.,Sun, Y.,Shen, XQ.,Chen, X.,Yao, WR.,...&Pei, RJ.(2015).Quantification of Zn(II) using a label-free sensor based on graphene oxide and G-quadruplex.ANALYTICAL METHODS,7(22),4. |
| MLA | Guo, YH,et al."Quantification of Zn(II) using a label-free sensor based on graphene oxide and G-quadruplex".ANALYTICAL METHODS 7.22(2015):4. |
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