Titanium isopropoxide complexes supported by pyrrolyl Schiff base ligands: syntheses, structures, and antitumor activity
文献类型：期刊论文
| 作者 | Lin, MS (Lin, Miaoshui) ; Cao, YH (曹玉华) ; Pei, H (Pei, Hao) ; Chen, YM (Chen, Yanmei) ; Wu, J (Wu, Jian) ; Li, YH (Li, Yahong) ; Liu, W (Liu, Wei) |
| 刊名 | RSC ADVANCES
 |
| 出版日期 | 2014 |
| 卷号 | 4期号:18页码:9255-9260 |
| 关键词 | PLATINUM DERIVATIVES REACTIVITY |
| 通讯作者 | Li, YH (Li, Yahong) |
| 英文摘要 | The syntheses, structures and antitumor activity of four titanium isopropoxide complexes supported by pyrrolyl Schiff base ligands are reported. Treatment of Ti(OPr)(4) with 2 equivalents of HL1 (HL1 = N-(1H-pyrrol- 2-ylmethylene)(2-pyridinyl)methanimine), HL2 ( HL2 = 2-pyrrolecarbaldmethylimine), HL3 (HL3 = N-((1H-pyrrol-2-yl)methylene)(phenyl)methanimine) and HL4 (HL4 = N-((1H-pyrrol-2-yl)methylene)-2-phenylethanimine), respectively, results in the formation of Ti(OPr)(2)(L1)(2) (1), Ti(OiPr)(2)(L2)(2) (2), Ti(OiPr)(2)(L3)(2) (3) and Ti(OiPr)(2)(L4)(2) (4). All complexes have been characterized by elemental analyses and NMR studies. The solid-state structures of complexes 1 and 3 have been further established by single X-ray crystallography. The cytotoxicity activities of 1-4 towards the tumor cells HCT-116, PC3 and MCF-7 were measured. Complexes 1, 2 and 3 showed good antitumor properties. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000330800700048 |
| 公开日期 | 2014-12-19 |
| 源URL | [http://ir.sinano.ac.cn/handle/332007/1693]  |
| 专题 | 苏州纳米技术与纳米仿生研究所_纳米生物医学与安全研究部_张智军团队 |
| 推荐引用方式 GB/T 7714 | Lin, MS ,Cao, YH ,Pei, H ,et al. Titanium isopropoxide complexes supported by pyrrolyl Schiff base ligands: syntheses, structures, and antitumor activity[J]. RSC ADVANCES,2014,4(18):9255-9260. |
| APA | Lin, MS .,Cao, YH .,Pei, H .,Chen, YM .,Wu, J .,...&Liu, W .(2014).Titanium isopropoxide complexes supported by pyrrolyl Schiff base ligands: syntheses, structures, and antitumor activity.RSC ADVANCES,4(18),9255-9260. |
| MLA | Lin, MS ,et al."Titanium isopropoxide complexes supported by pyrrolyl Schiff base ligands: syntheses, structures, and antitumor activity".RSC ADVANCES 4.18(2014):9255-9260. |
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