Heterogeneity in cancer stem cells
文献类型:期刊论文
作者 | Wang, AX(王安欣); Chen, LS(陈丽莎); Li, CL(李春林); Zhu, YM(朱毅敏)![]() |
刊名 | CANCER LETTERS
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出版日期 | 2015 |
卷号 | 357期号:1页码:6 |
关键词 | Cancer stem cell Heterogeneity Surface marker Targeting therapy |
通讯作者 | Zhu, YM (朱毅敏) |
英文摘要 | Accumulating evidence suggests that cancer stem cells (CSCs) are heterogeneous populations and their phenotypes are unstable. A number of intrinsic and extrinsic mechanisms contribute to CSC phenotypic variation. The existence of various CSC subpopulations which would lead to a rapid relapse after primary treatments might pose a problem for CSC targeted therapeutics. In order to develop more effective approaches to cancer therapeutics, more CSC-related surface markers or targeting molecules, as well as some novel targeting strategies should be explored. This review summarized the origin and performance of heterogeneity in CSCs and discussed their therapeutic implications. (c) 2014 Elsevier Ireland Ltd. All rights reserved. |
收录类别 | SCI |
语种 | 英语 |
源URL | [http://ir.sinano.ac.cn/handle/332007/3441] ![]() |
专题 | 苏州纳米技术与纳米仿生研究所_纳米生物医学与安全研究部_朱毅敏团队 |
推荐引用方式 GB/T 7714 | Wang, AX,Chen, LS,Li, CL,et al. Heterogeneity in cancer stem cells[J]. CANCER LETTERS,2015,357(1):6. |
APA | Wang, AX,Chen, LS,Li, CL,&Zhu, YM.(2015).Heterogeneity in cancer stem cells.CANCER LETTERS,357(1),6. |
MLA | Wang, AX,et al."Heterogeneity in cancer stem cells".CANCER LETTERS 357.1(2015):6. |
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