Process for Glycine Production by Antisolvent Crystallization Using Its Phase Equilibria in the Ethylene Glycol-NH4Cl-Water System
文献类型：期刊论文
| 作者 | Zeng, Yan1,2; Li, Zhibao1; Demopoulos, George P.2 |
| 刊名 | INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
 |
| 出版日期 | 2016-03-02 |
| 卷号 | 55期号:8页码:2426-2437 |
| 关键词 | AQUEOUS SALT SYSTEMS ANHYDROUS SODIUM-CARBONATE PARTIAL MOLAL PROPERTIES LIQUID-SOLID EQUILIBRIA EXTENDED UNIQUAC MODEL EXCESS GIBBS ENERGY AMINO-ACIDS TRANSPORT-PROPERTIES ELECTROLYTE SYSTEMS HIGH-PRESSURES |
| ISSN号 | 0888-5885 |
| 通讯作者 | Li, ZB (reprint author), Chinese Acad Sci, Inst Proc Engn, Key Lab Green Proc & Engn, Beijing 100190, Peoples R China. |
| 英文摘要 | A new process for the production of glycine by using antisolvent crystallization with the mixture of ethylene glycol (MEG) and water as a substitute for methanol has been developed on the basis of chemical modeling phase equilibria for the glycineNH(4)ClMEGH(2)O system. MEG is considered as a green solvent because it has great higher boiling point up to 470 K and thus is almost nonvolatile compared with methanol. We discovered that the solubility of glycine, NH4Cl and their mixtures can be greatly changed by altering the composition of the mixed MEG-H2O solvents and realized the complete separation of glycine and NH4Cl by water evaporation. Phase equilibria for the glycine NH4Cl-MEG-H2O system were measured from 278 to 353 K. The mixed-solvent electrolyte (MSE) model was applied with new binary interaction parameters obtained from regressing experimental and literature data. This newly modified model accurately predicted the solubilities in the quaternary glycine NH4Cl-MEG-H2O system with average absolute relative deviations of 5.84% and 1.03% for glycine and NH4Cl, respectively. Simulation for the new process was performed by the model to investigate its operating conditions, from which the optimal composition of antisolvent was determined to be 50 wt % of MEG solution. Under this condition, glycine and NH4Cl were successfully separated from their solid mixtures in batch crystallization experiments, validating the feasibility of the proposed process for glycine production. |
| WOS标题词 | Science & Technology ; Technology |
| 学科主题 | Engineering, Chemical ; Engineering |
| 类目[WOS] | Engineering, Chemical |
| 研究领域[WOS] | Engineering |
| 关键词[WOS] | AQUEOUS SALT SYSTEMS ; ANHYDROUS SODIUM-CARBONATE ; PARTIAL MOLAL PROPERTIES ; LIQUID-SOLID EQUILIBRIA ; EXTENDED UNIQUAC MODEL ; EXCESS GIBBS ENERGY ; AMINO-ACIDS ; TRANSPORT-PROPERTIES ; ELECTROLYTE SYSTEMS ; HIGH-PRESSURES |
| 收录类别 | SCI |
| 原文出处 | AMER CHEMICAL SOC |
| 语种 | 英语 |
| WOS记录号 | WOS:000371453800016 |
| 源URL | [http://ir.ipe.ac.cn/handle/122111/20688]  |
| 专题 | 过程工程研究所_研究所（批量导入） |
| 作者单位 | 1.Chinese Acad Sci, Inst Proc Engn, Key Lab Green Proc & Engn, Beijing 100190, Peoples R China 2.McGill Univ, Dept Min & Mat Engn, 3610 Univ St, Montreal, PQ H3A 2B2, Canada |
| 推荐引用方式 GB/T 7714 | Zeng, Yan,Li, Zhibao,Demopoulos, George P.. Process for Glycine Production by Antisolvent Crystallization Using Its Phase Equilibria in the Ethylene Glycol-NH4Cl-Water System[J]. INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH,2016,55(8):2426-2437. |
| APA | Zeng, Yan,Li, Zhibao,&Demopoulos, George P..(2016).Process for Glycine Production by Antisolvent Crystallization Using Its Phase Equilibria in the Ethylene Glycol-NH4Cl-Water System.INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH,55(8),2426-2437. |
| MLA | Zeng, Yan,et al."Process for Glycine Production by Antisolvent Crystallization Using Its Phase Equilibria in the Ethylene Glycol-NH4Cl-Water System".INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH 55.8(2016):2426-2437. |
入库方式： OAI收割
来源：过程工程研究所
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