Synthesis of a highly fluorescence nitrogen-doped carbon quantum dots bioimaging probe and its in vivo clearance and printing applications
文献类型：期刊论文
| 作者 | Parvin, Nargish1,3; Mandal, Tapas K.2,3 |
| 刊名 | RSC ADVANCES
 |
| 出版日期 | 2016 |
| 卷号 | 6期号:22页码:18134-18140 |
| 关键词 | COATED GOLD NANOPARTICLES SENSITIVE DETECTION FACILE SYNTHESIS RENAL CLEARANCE GRAPHENE OXIDE NANODOTS TOXICITY IONS SIZE BIODISTRIBUTION |
| ISSN号 | 2046-2069 |
| 通讯作者 | Mandal, TK (reprint author), Chinese Acad Sci, Inst Chem, Bei Yi Jie 2, Beijing 100190, Peoples R China. |
| 英文摘要 | Highly fluorescent, broad range pH and ionic-stable N-doped carbon quantum dots (N-CQDs) were successfully synthesized and their chemical structure and fluorescence mechanism were characterized. Mono-dispersed N-CQDs averaging 4.5 nm in diameter were achieved in a quantum yield (QY) of 74.16%. These N-CQDs showed great potential in biomedical and optical imaging applications both in vivo and in vitro. Biodistribution, retention, toxicity, and pharmacokinetics profiles are mandatory in their potential clinical applications. Herein, the biodistribution, clearance, and toxicity of our invariable N-CQDs species were systematically investigated over 7 days in mice. Most of the N-CQDs were cleared at 6 days post-injection without any accumulation in any vital organs or tissues. Moreover, the high fluorescence N-CQDs were demonstrated to be effective as printing inks for multicolour patterns. This study suggests that N-CQDs may be an attractive alternative to metal quantum dots for secure biomedical and other industrial applications. |
| WOS标题词 | Science & Technology ; Physical Sciences |
| 学科主题 | Chemistry, Multidisciplinary ; Chemistry |
| 类目[WOS] | Chemistry, Multidisciplinary |
| 研究领域[WOS] | Chemistry |
| 关键词[WOS] | COATED GOLD NANOPARTICLES ; SENSITIVE DETECTION ; FACILE SYNTHESIS ; RENAL CLEARANCE ; GRAPHENE OXIDE ; NANODOTS ; TOXICITY ; IONS ; SIZE ; BIODISTRIBUTION |
| 收录类别 | SCI |
| 原文出处 | ROYAL SOC CHEMISTRY |
| 语种 | 英语 |
| WOS记录号 | WOS:000370717900040 |
| 源URL | [http://ir.ipe.ac.cn/handle/122111/20708]  |
| 专题 | 过程工程研究所_研究所（批量导入） |
| 作者单位 | 1.Chinese Acad Sci, Inst Proc Engn, Key Lab Biochem Engn, 1 Bei Erjie, Beijing 100190, Peoples R China 2.Chinese Acad Sci, Inst Chem, Bei Yi Jie 2, Beijing 100190, Peoples R China 3.Indian Inst Technol, Dept Biotechnol, Roorkee 247667, Uttar Pradesh, India |
| 推荐引用方式 GB/T 7714 | Parvin, Nargish,Mandal, Tapas K.. Synthesis of a highly fluorescence nitrogen-doped carbon quantum dots bioimaging probe and its in vivo clearance and printing applications[J]. RSC ADVANCES,2016,6(22):18134-18140. |
| APA | Parvin, Nargish,&Mandal, Tapas K..(2016).Synthesis of a highly fluorescence nitrogen-doped carbon quantum dots bioimaging probe and its in vivo clearance and printing applications.RSC ADVANCES,6(22),18134-18140. |
| MLA | Parvin, Nargish,et al."Synthesis of a highly fluorescence nitrogen-doped carbon quantum dots bioimaging probe and its in vivo clearance and printing applications".RSC ADVANCES 6.22(2016):18134-18140. |
入库方式： OAI收割
来源：过程工程研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。