Molecular Engineering of Aqueous Soluble Triarylboron-Compound-Based Two-Photon Fluorescent Probe for Mitochondria H2S with Analyte-Induced Finite Aggregation and Excellent Membrane Permeability
文献类型：期刊论文
| 作者 | Liu, Jun1; Guo, Xudong1; Hu, Rui1; Liu, Xinyang2; Wang, Shuangqing1; Li, Shayu1; Li, Yi2; Yang, Guoqiang1 |
| 刊名 | ANALYTICAL CHEMISTRY
 |
| 出版日期 | 2016-01-05 |
| 卷号 | 88期号:1页码:1052-1057 |
| 英文摘要 | Hydrogen sulfide (H2S) is a multifunctional signaling molecule that participates in many important biological processes. Herein, by functionalizing triarylboron with cyclen and diphenylamine, we synthesized TAB-1, TAB-2, and TAB-3 for H2S recongnization by rational design of molecular structures. Among them, aqueous soluble TAB-2 possesses excellent properties, including large two-photon action cross section, membrane permeability and can effectively complex with Cu2+ The complex of TAB-2-Cu2+ can selectively detect H2S with an instant response and mitochondria targeted. Moreover, the H2S-induced finite aggregation of indicators enhances their photostability and causes variation of the fluorescence lifetime. TAB-2-Cu2+ has also been successfully applied for the mitochondria H2S imaging in NIH/3T3 fibroblast cells by TPM and FLIM. |
| 收录类别 | SCI |
| 语种 | 英语 |
| 公开日期 | 2016-05-09 |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/29776]  |
| 专题 | 化学研究所_光化学实验室 |
| 作者单位 | 1.Chinese Acad Sci, Inst Chem, Key Lab Photochem, Beijing Natl Lab Mol Sci, Beijing 100190, Peoples R China 2.Chinese Acad Sci, Tech Inst Phys & Chem, Key Lab Photochem Convers & Optoelect Mat, Beijing 100190, Peoples R China |
| 推荐引用方式 GB/T 7714 | Liu, Jun,Guo, Xudong,Hu, Rui,et al. Molecular Engineering of Aqueous Soluble Triarylboron-Compound-Based Two-Photon Fluorescent Probe for Mitochondria H2S with Analyte-Induced Finite Aggregation and Excellent Membrane Permeability[J]. ANALYTICAL CHEMISTRY,2016,88(1):1052-1057. |
| APA | Liu, Jun.,Guo, Xudong.,Hu, Rui.,Liu, Xinyang.,Wang, Shuangqing.,...&Yang, Guoqiang.(2016).Molecular Engineering of Aqueous Soluble Triarylboron-Compound-Based Two-Photon Fluorescent Probe for Mitochondria H2S with Analyte-Induced Finite Aggregation and Excellent Membrane Permeability.ANALYTICAL CHEMISTRY,88(1),1052-1057. |
| MLA | Liu, Jun,et al."Molecular Engineering of Aqueous Soluble Triarylboron-Compound-Based Two-Photon Fluorescent Probe for Mitochondria H2S with Analyte-Induced Finite Aggregation and Excellent Membrane Permeability".ANALYTICAL CHEMISTRY 88.1(2016):1052-1057. |
入库方式： OAI收割
来源：化学研究所
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