中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
The Directional Observation of Highly Dynamic Membrane Tubule Formation Induced by Engulfed Liposomes

文献类型:期刊论文

作者Zhang, Xiaoming1,2; Dai, Luru1; Wang, Anhe1; Woelk, Christian3; Dobner, Bodo3; Brezesinski, Gerald4; Tang, Yunqing1,5; Wang, Xianyou1,5; Li, Junbai1,2
刊名SCIENTIFIC REPORTS
出版日期2015-11-09
卷号5
英文摘要Highly dynamic tubular structures in cells are responsible for exchanges between organelles. Compared with bacterial invasion, the most affordable and least toxic lipids were found in this study to be gentle and safe exogenous stimuli for the triggering of membrane tubules. A specific lipid system was internalized by NIH3T3 cells. Following cellular uptake, the constructed liposomes traveled towards the nucleus in aggregations and were gradually distributed into moving vesicles and tubules in the cytosol. The triggered tubules proceeded, retreated or fluctuated along the cytoskeleton and were highly dynamic, moving quickly (up to several microns per second), and breaking and fusing frequently. These elongated tubules could also fuse with one another, giving rise to polygonal membrane networks. These lipid systems, with the novel property of accelerating intracellular transport, provide a new paradigm for investigating cellular dynamics.
收录类别SCI
语种英语
公开日期2016-05-09
源URL[http://ir.iccas.ac.cn/handle/121111/29195]  
专题化学研究所_胶体、界面与化学热力学实验室
作者单位1.Natl Ctr Nanosci & Technol, Beijing 100190, Peoples R China
2.Chinese Acad Sci, Inst Chem, CAS Key Lab Colloid Interface & Chem Thermodynam, Natl Lab Mol Sci, Beijing 100190, Peoples R China
3.Univ Halle Wittenberg, Inst Pharm, D-06120 Halle, Saale, Germany
4.Max Planck Inst Colloids & Interfaces, D-14476 Potsdam, Germany
5.Chinese Acad Sci, Inst Theoret Phys, Beijing 100190, Peoples R China
推荐引用方式
GB/T 7714
Zhang, Xiaoming,Dai, Luru,Wang, Anhe,et al. The Directional Observation of Highly Dynamic Membrane Tubule Formation Induced by Engulfed Liposomes[J]. SCIENTIFIC REPORTS,2015,5.
APA Zhang, Xiaoming.,Dai, Luru.,Wang, Anhe.,Woelk, Christian.,Dobner, Bodo.,...&Li, Junbai.(2015).The Directional Observation of Highly Dynamic Membrane Tubule Formation Induced by Engulfed Liposomes.SCIENTIFIC REPORTS,5.
MLA Zhang, Xiaoming,et al."The Directional Observation of Highly Dynamic Membrane Tubule Formation Induced by Engulfed Liposomes".SCIENTIFIC REPORTS 5(2015).

入库方式: OAI收割

来源:化学研究所

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