Layer by layer assembly of albumin nanoparticles with selective recognition of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)
文献类型：期刊论文
| 作者 | Cui, Wei1; Wang, Anhe2; Zhao, Jie1; Yang, Xiaoke1; Cai, Peng1; Li, Junbai1,2 |
| 刊名 | JOURNAL OF COLLOID AND INTERFACE SCIENCE
 |
| 出版日期 | 2016-03-01 |
| 卷号 | 465页码:11-17 |
| 关键词 | Layer-by-layer Nanoparticles Albumin TRAIL Core-shell |
| 英文摘要 | Crosslinked albumin nanoparticles which loaded with doxorubicin (DOX) were fabricated with tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and biocompatible polysaccharide, alginate (ALG), using layer-by-layer technique. Albumin nanoparticles exhibited narrow size distribution and fluorescent property. The assembled core/shell structure of the nanoparticles can be internalized more easily with the cancer cells, which attributes to TRAIL binding with death receptors. TRAIL still hold bioactive properties after assembled onto the particles. In addition, after loaded into the albumin core nanoparticles, DOX (as the chemotherapeutics) display a synergistic cytotoxic effect on cytotoxicity in combination with TRAIL in vitro. The core/shell nanostructured nanoparticles realized in this study would be used as a promising candidate for novel drug carriers. (C) 2015 Elsevier Inc. All rights reserved. |
| 收录类别 | SCI |
| 语种 | 英语 |
| 公开日期 | 2016-05-09 |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/29779]  |
| 专题 | 化学研究所_胶体、界面与化学热力学实验室 |
| 作者单位 | 1.Chinese Acad Sci, Beijing Natl Lab Mol Sci, CAS Key Lab Colloid Interface & Chem Thermodynam, Inst Chem, Beijing 100190, Peoples R China 2.Natl Ctr Nanosci & Technol, Beijing 100190, Peoples R China |
| 推荐引用方式 GB/T 7714 | Cui, Wei,Wang, Anhe,Zhao, Jie,et al. Layer by layer assembly of albumin nanoparticles with selective recognition of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)[J]. JOURNAL OF COLLOID AND INTERFACE SCIENCE,2016,465:11-17. |
| APA | Cui, Wei,Wang, Anhe,Zhao, Jie,Yang, Xiaoke,Cai, Peng,&Li, Junbai.(2016).Layer by layer assembly of albumin nanoparticles with selective recognition of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL).JOURNAL OF COLLOID AND INTERFACE SCIENCE,465,11-17. |
| MLA | Cui, Wei,et al."Layer by layer assembly of albumin nanoparticles with selective recognition of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)".JOURNAL OF COLLOID AND INTERFACE SCIENCE 465(2016):11-17. |
入库方式： OAI收割
来源：化学研究所
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