Synthesis and labeling of alpha-(2,9)-trisialic acid with cyanine dyes for imaging of glycan-binding receptors on living cells
文献类型：期刊论文
| 作者 | Zhang, Xiao-tai1; Gu, Zhen-yuan1; Liu, Libing2; Wang, Shu2; Xing, Guo-wen1 |
| 刊名 | CHEMICAL COMMUNICATIONS
 |
| 出版日期 | 2015 |
| 卷号 | 51期号:41页码:8606-8609 |
| 英文摘要 | A sugar epitope, alpha-(2,9)-trisialic acid, was synthesized and labeled by cyanine dyes through Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC). The cyanine tagged oligosialic acid can be utilized as an efficient fluorescent probe to image the glycan-binding receptors on PC-12 cells. The distribution of Sia-binding immunoglobulin-like lectins (Siglecs) for alpha-(2,9)-trisialic acid was visualized by Cy3/Cy5 or FRET channel fluorescence imaging. |
| 收录类别 | SCI |
| 语种 | 英语 |
| 公开日期 | 2016-05-09 |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/28015]  |
| 专题 | 化学研究所_有机固体实验室 |
| 作者单位 | 1.Beijing Normal Univ, Dept Chem, Beijing 100875, Peoples R China 2.Chinese Acad Sci, Inst Chem, Key Lab Organ Solids, Beijing 100190, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Xiao-tai,Gu, Zhen-yuan,Liu, Libing,et al. Synthesis and labeling of alpha-(2,9)-trisialic acid with cyanine dyes for imaging of glycan-binding receptors on living cells[J]. CHEMICAL COMMUNICATIONS,2015,51(41):8606-8609. |
| APA | Zhang, Xiao-tai,Gu, Zhen-yuan,Liu, Libing,Wang, Shu,&Xing, Guo-wen.(2015).Synthesis and labeling of alpha-(2,9)-trisialic acid with cyanine dyes for imaging of glycan-binding receptors on living cells.CHEMICAL COMMUNICATIONS,51(41),8606-8609. |
| MLA | Zhang, Xiao-tai,et al."Synthesis and labeling of alpha-(2,9)-trisialic acid with cyanine dyes for imaging of glycan-binding receptors on living cells".CHEMICAL COMMUNICATIONS 51.41(2015):8606-8609. |
入库方式： OAI收割
来源：化学研究所
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