Topographical Binding to Mucosa-Exposed Cancer Cells: Pollen-Mimetic Porous Microspheres with Tunable Pore Sizes
文献类型：期刊论文
| 作者 | Feng, Jiantao1,3; Lin, Ling2,4; Chen, Peipei3; Hua, Wenda3,5; Sun, Quanmei3; Ao, Zhuo3; Liu, Dongsheng1; Jiang, Lei4; Wang, Shutao4; Han, Dong3 |
| 刊名 | ACS APPLIED MATERIALS & INTERFACES
 |
| 出版日期 | 2015-05-06 |
| 卷号 | 7期号:17页码:8961-8967 |
| 关键词 | microsphere adhesive topographical binding mucosa cancer cell |
| 英文摘要 | Mucoadhesives have been perceived as an effective approach for targeting the mucosa-associated diseases, which relied on the adhesive molecules to enhance the specificity. Here, topographical binding is proposed based on the fabrication of surface pore size tunable pollen-mimetic microspheres with phase separation and electrospray technology. We proved that microspheres with large-pores (pore size of 1005 +/- 448 nm) were the excellent potential candidate for the mucoadhesives) as they not only possessed better adhesion ability, but also could topographically bind cervical cancer cells. Our methods of topographical binding offered a new way of designing the mucoadhesives for treating the mucosa-associated diseases. |
| 收录类别 | SCI |
| 语种 | 英语 |
| 公开日期 | 2016-05-09 |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/28104]  |
| 专题 | 化学研究所_有机固体实验室 |
| 作者单位 | 1.Tsinghua Univ, Dept Chem, Key Lab Organ Optoelect & Mol Engn, Minist Educ, Beijing 100084, Peoples R China 2.State Ocean Adm, Inst Oceanog 3, Engn Res Ctr Marine Biol Resource Comprehens Util, Xiamen 361005, Peoples R China 3.Natl Ctr Nanosci & Technol, Beijing 100190, Peoples R China 4.Chinese Acad Sci, Beijing Natl Lab Mol Sci BNLMS, Inst Chem, Key Lab Organ Solids, Beijing 100190, Peoples R China 5.Kunming Med Univ, Affiliated Hosp 1, Kunming 650032, Peoples R China |
| 推荐引用方式 GB/T 7714 | Feng, Jiantao,Lin, Ling,Chen, Peipei,et al. Topographical Binding to Mucosa-Exposed Cancer Cells: Pollen-Mimetic Porous Microspheres with Tunable Pore Sizes[J]. ACS APPLIED MATERIALS & INTERFACES,2015,7(17):8961-8967. |
| APA | Feng, Jiantao.,Lin, Ling.,Chen, Peipei.,Hua, Wenda.,Sun, Quanmei.,...&Han, Dong.(2015).Topographical Binding to Mucosa-Exposed Cancer Cells: Pollen-Mimetic Porous Microspheres with Tunable Pore Sizes.ACS APPLIED MATERIALS & INTERFACES,7(17),8961-8967. |
| MLA | Feng, Jiantao,et al."Topographical Binding to Mucosa-Exposed Cancer Cells: Pollen-Mimetic Porous Microspheres with Tunable Pore Sizes".ACS APPLIED MATERIALS & INTERFACES 7.17(2015):8961-8967. |
入库方式： OAI收割
来源：化学研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。