Near-infrared absorbing mesoporous carbon nanoparticle as an intelligent drug carrier for dual-triggered synergistic cancer therapy
文献类型：期刊论文
| 作者 | Zhou,Li; Dong,Kai; Chen,Zhaowei; Ren,Jinsong; Qu,Xiaogang |
| 刊名 | carbon
 |
| 出版日期 | 2015 |
| 卷号 | 82页码:479-488 |
| 关键词 | GUIDED PHOTOTHERMAL THERAPY GRAPHENE OXIDE HYALURONIC-ACID MAGNETIC NANOPARTICLES SILICA NANOPARTICLES THERMO-CHEMOTHERAPY GOLD NANOPARTICLES DELIVERY VEHICLE IRON-OXIDE CELLS |
| 通讯作者 | ren,js |
| 英文摘要 | herein a novel multifunctional nanoplatform based on surface engineered mesoporous carbon nanoparticle (mcn) is developed for effective dual-triggered synergistic cancer therapy. mcns employed in the study not only function as near-infrared absorbing agents but also as nanocarriers with a high drug loading efficiency. the surface modification of mcn with biomacromolecules (hyaluronic acid) through disulfide unit makes the system be sensitive to both intracellular hyaluronidase-1 and gsh to release the carried drug. the hyaluronic acid on mcn simultaneously confers the system biocompatibility and a cancer cell targeting ability. by combining these capabilities, the multifunctional nanoplatform shows an effective therapeutic efficiency toward the target cells. (c) 2014 elsevier ltd. all rights reserved. |
| 收录类别 | SCI |
| 语种 | 英语 |
| 公开日期 | 2016-05-09 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/64796]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Zhou,Li,Dong,Kai,Chen,Zhaowei,et al. Near-infrared absorbing mesoporous carbon nanoparticle as an intelligent drug carrier for dual-triggered synergistic cancer therapy[J]. carbon,2015,82:479-488. |
| APA | Zhou,Li,Dong,Kai,Chen,Zhaowei,Ren,Jinsong,&Qu,Xiaogang.(2015).Near-infrared absorbing mesoporous carbon nanoparticle as an intelligent drug carrier for dual-triggered synergistic cancer therapy.carbon,82,479-488. |
| MLA | Zhou,Li,et al."Near-infrared absorbing mesoporous carbon nanoparticle as an intelligent drug carrier for dual-triggered synergistic cancer therapy".carbon 82(2015):479-488. |
入库方式： OAI收割
来源：长春应用化学研究所
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