Electrospun PLA/MWCNTs composite nanofibers for combined chemo- and photothermal therapy
文献类型：期刊论文
| 作者 | Zhang,Z.; Liu,S.; Xiong,H.; Jing,X.; Xie,Z.; Chen,X.; Huang,Y. |
| 刊名 | acta biomaterialia
 |
| 出版日期 | 2015 |
| 卷号 | 26期号:20页码:115-123 |
| 关键词 | DRUG-DELIVERY BIOMEDICAL APPLICATIONS CARBON NANOTUBES CANCER-TREATMENT NANOPARTICLES RELEASE STRATEGIES CARCINOMA SYSTEM WAFERS |
| 通讯作者 | huang,y |
| 英文摘要 | carbon nanotubes are effective thermal generators by absorbing near-infrared radiation (nir). in this study, multiwalled carbon nanotubes (mwcnts) and doxorubicin (dox) were successfully electrospun into the poly-i.-lactic acid (plla) nanofibers. it is confirmed that nir radiation could not only initiate burst release of dox from the fibers due to the relatively low glass transition temperature (t-g) of plla, but also significantly increase the temperature of fibers-covering tumor site. the multifunctional fibers showed increased cytotoxicity both in vitro and in vivo by the combination of photothermal induced hyperthermia and chemotherapy with dox. this drug delivery system could be very useful and convenient in future clinical applications for localized cancer therapy. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000362917200012 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/64804]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Zhang,Z.,Liu,S.,Xiong,H.,et al. Electrospun PLA/MWCNTs composite nanofibers for combined chemo- and photothermal therapy[J]. acta biomaterialia,2015,26(20):115-123. |
| APA | Zhang,Z..,Liu,S..,Xiong,H..,Jing,X..,Xie,Z..,...&Huang,Y..(2015).Electrospun PLA/MWCNTs composite nanofibers for combined chemo- and photothermal therapy.acta biomaterialia,26(20),115-123. |
| MLA | Zhang,Z.,et al."Electrospun PLA/MWCNTs composite nanofibers for combined chemo- and photothermal therapy".acta biomaterialia 26.20(2015):115-123. |
入库方式： OAI收割
来源：长春应用化学研究所
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